Out of total 25 patients with cutaneous drug reactions, morbilliform rash
was the most common (Figure 3).
A relative of dengue, the chikungunya virus can present in the form of a morbilliform rash
, nasal hyperpigmentation, purpuric macules, and erythema, the latter of which can sometimes be accompanied by ulcers.
Various morphologies ranging from morbilliform rash
to Stevens-Johnson syndrome and toxic epidermal necrolysis may occur.
7 A morbilliform rash
is the most common reaction to phenytoin occurring in as many as 5% of cases overall.
Classification of beta-lactam reactions by the time between administration of the drug and the reaction and by its relation with IgE (7,8) Early (<1 hour) and rapid reaction (1-72 hours) (IgE-mediated): Urticaria Laryngeal edema Bronchospasm Hypotension Regional swelling Delayed (after 72 hours): Morbilliform rash
Urticaria Severe delayed reactions (non-IgE-mediated): SJS TEN DRESS Interstitial nephritis Pulmonary involvement Vasculitis Hemolytic anemia SJS: Steven-Jonhson syndrome; TEN: toxic epidermal necrolysis; DRESS: drug rash eosinophilia and systemic sypmtoms Table 3.
When investigated by public health officials on April 6, the patient had a morbilliform rash
, cough, coryza, conjunctivitis, and Koplik spots, and reported no recent travel or contact with ill persons.
6) For this study, the following were designated the 'classic dermatological measles syndrome': Koplik's spots, other typical oral manifestations (stomatitis), conjunctivitis, and a morbilliform rash
with cephalocaudal spread.
The patient had no history of enanthem (Koplik spots) or morbilliform rash
before or after symptom onset and no documented history of measles vaccination.
Be hypervigilant for the three C's plus high fever, and classic morbilliform rash
True (A) or false (B) - click on the correct answer: The morbilliform rash
of measles usually spares the palms and soles.
Accelerated and delayed reactions are not IgE-mediated and those affected may develop a morbilliform rash
, serum sickness, vasculitis, contact dermatitis, Stevens-Johnson syndrome or toxic epidermal necrolysis.
A morbilliform rash
appears, particularly on the face, accompanied by fever, adenopathy, and joint pain.