montelukast


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Related to montelukast: Montelukast sodium, Singulair

montelukast

 [mon″tĕ-loo´kast]
a leukotriene antagonist used as the sodium salt in prophylaxis and chronic treatment of asthma.

montelukast

/mon·te·lu·kast/ (mon″tĕ-loo´kast) a leukotriene antagonist used as the sodium salt in prophylaxis and chronic treatment of asthma.

montelukast

(mŏn′tə-lo͞o′kăst)
n.
A drug that reduces the inflammatory response by acting as a leukotriene receptor antagonist, and is used to treat the signs and symptoms of asthma.

montelukast

a leukotriene receptor.
indication It is used to treat chronic asthma.
contraindication Known hypersensitivity to this drug prohibits its use.
adverse effects Adverse effects include dizziness, fatigue, headache, abdominal pain, dyspepsia, abnormal liver function tests, rash, asthenia, influenza, cough, and nasal congestion.

montelukast

Singulair® Internal medicine A leukotriene receptor antagonist used to manage asthma. See Asthma.

montelukast

A drug that binds to the receptors for certain leukotrienes thus blocking both phases of the ASTHMA response. It is used in the treatment of asthma that shows an inadequate response to inhaled steroids. A brand name is Singulair.

Montelukast (Singulair)

An inhibitor that prevents leukotrienes from binding to cell receptors; taken over time, montelukast can reduce or prevent symptoms of asthma and allergies.
References in periodicals archive ?
Montelukast is an oral medication that may be given to children with recurrent wheezing.
Montelukast is a CysLT1 antagonist that blocks the action of leukotriene D4 on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it.
Half of the children were given Salmeterol inhalers and half took Montelukast pills over the course of a year.
Major Finding: Of 25 medications tested, 16 were found to inhibit the metabolism of 17R Those with the strongest inhibitory effects were the asthma drug montelukast, and the protease inhibitors nelfinavir and ritonavir, which were associated with 90%-100% inhibition of 17P.
Pharmacogenetics of the 5-lipoxygenase biosynthetic pathway and variable clinical response to montelukast.
In humans, a randomized, controlled study by Combs showed that the leukotriene receptor antagonist montelukast in combination with amoxicillin was significantly more efficacious in clearing persistent OME than was amoxicillin and placebo (clearance rates: 58 and 16%, respectively).
The rats were treated with montelukast (10 mg kg[sup.
Montelukast has no effect on the clinical course of bronchiolitis or its outcome.
For all other asthma and COPD patients, concomitant therapies (eg, montelukast, formoterol or salmeterol DPI, theophylline) remained the same during the transition to BIS.
Montelukast, alerjik rinit ve astim tedavisinde eriskinde 10 mg /gun dozda kullanim icin lisansi olan selektif bir Cys LT reseptor antagonistidir (6).
Montelukast, the leukotriene receptor antagonist (LTRA), may prevent recurrence of non-asthmatic wheezing in young children where viruses are involved, (7-9) but the evidence is not yet complete.
The new treatment contains a four milligram dose of the drug montelukast, a non-steroid.