monotherapy


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monotherapy

/mono·ther·a·py/ (-ther´ah-pe) treatment of a condition by means of a single drug.

monotherapy

(mŏn′ō-thĕr′ə-pē)
n. pl. monothera·pies
1. The treatment of a medical disorder with a single drug.
2. A type or instance of such treatment: evaluating antimalarial monotherapies.

monotherapy

[mon′ōther′əpē]
Etymology: Gk, monos, single + therapeia, treatment
treatment of a condition by means of a single drug.

monotherapy

Single drug therapy or treatment Therapeutics The management of a particular condition–eg, HTN, with a single agent. See Hypertension. Cf Polypharmacy.
References in periodicals archive ?
These data provide rationale for Rgenix's ongoing Phase 1a/b trial of RGX-104 in advanced cancer patients and support evaluation of RGX-104 as both a monotherapy as well as in combination with CPIs.
Biopharmaceutical company UCB reported on Thursday the receipt of approval from the US Food and Drug Administration (FDA) for its supplemental new drug application (sNDA) for BRIVIACT (brivaracetam) CV monotherapy indication for partial-onset (focal) seizures (POS) in patients 16 years and older with epilepsy.
ORAL Strategy is a bold study that directly compared XELJANZ as a monotherapy or in combination with methotrexate to Humira in combination with methotrexate, said Michael Corbo, Chief Development Officer, Inflammation & Immunology, Pfizer Global Product Development.
001), compared with its monotherapy components and placebo, according to AstraZeneca's statement.
Maruthur and her associates conducted an update of a previous systematic literature review and meta-analysis to assess the comparative effectiveness and safety of metformin monotherapy and combination therapies including metformin with nonmetformin monotherapies in patients with type 2 diabetes.
The most common adverse event was fever, experienced by 53% of patients in the combination arm and 21% of patients in the monotherapy arm; however, there were more grade 3 and 4 adverse events noted among patients treated with vemurafenib alone.
In the PREMIER trial, the addition of adalimumab to MTX therapy proved more effective than switching to adalimumab monotherapy for all measures of response, including radiographic progression.
2% of the tocilizumab monotherapy group achieving remission by week 8.
However, an ACE-I combined with an ARB increases the risk of renal complications and death more than monotherapy (SOR: A, RCT).
The majority of the women (504) were on AED monotherapy.
As a result, they were virtually being treated with protease-inhibitor monotherapy.
Clarithromycin has been administered successfully as monotherapy, and our case confirms these data.