Gs-alpha gene mutations in monostotic
fibrous dysplasia of bone and fibrous dysplasia-like low-grade central osteosarcoma.
vertebral Paget's disease of the lumbar spine.
Summary of patients with fibrous dysplasia (n=25) Sr Age (yr) at Sex Bone Endocrinopathy Cafe-au-lait no presentation involvement macules (poly/mono) 1 11 F P - + 2 24 F P - - 3 30 F P Hyperthyroidism - 4 28 M P Acromegaly - 5 25 M P Acromegaly - 6 40 M P Acromegaly - 7 19 F P Hypophosphatemic + rickets 8 17 F P - - 9 22 F M - - 10 11 M M - + 11 15 M M - - 12 22 F P - - 13 10 M P - - 14 19 F P - - 15 14 F M - - 16 19 F P - - 17 48 M P Acromegaly + 18 38 M M Acromegaly - 19 30 M M - - 20 32 M M - - 21 23 M P - - 22 44 F P - - 23 15 M P - - 24 42 M P - - 25 7 F P Precocious + puberty, hyperthyroidism M, male; F, female; P, polystotic; M, monostotic
and polyostotic forms share the same radiographic appearance, histologic features, and anatomic sites of involvement, but the mandible is often more-commonly affected in monostotic
forms, and long bone involvement prevails in polyostotic FD.
In our review of the literature, eight of the reported patients had cafe-au-lait macules, only four of them had monostotic
Twelve patients with monostotic
Paget's disease of bone underwent 1-hour dynamic [.
fibrous dysplasia accounts for approximately 70% of all cases, and it usually involves one of the long bones.
In this article, we describe a case of monostotic
fibrous dysplasia in a middle-aged woman who responded well to medical treatment.
fibrous dysplasia originating from ethmoid bone: Treatment with endoscopic approach.
com 2,3,4 FETAL FACE SYNDROME See: Robinow Syndrome FETAL IRITIS SYNDROME See: Norrie Disease FIBROMYALGIA See: Arthritis FIBROUS ANKYLOSIS OF MULTIPLE JOINTS See: Arthrogryposis Multiplex Congenita FIBROUS DYSPLASIA, MONOSTOTIC
See: McCune-Albright Syndrome FIBROUS DYSPLASIA, POLYOSTOTIC See: McCune-Albright Syndrome FIBULAR HEMIMELIA See: Limb Disorders FIRST AND SECOND BRANCHIAL ARCH SYNDROME See: Goldenhar Syndrome FISCHER SYNDROME See: Guillain-Barre Syndrome FISCHER-JACOBSEN-CLOUSTON SYNDROME See: Ectodermal Dysplasias FOCAL DERMAL HYPOPLASIA (FDH) SYNDROME See: Craniofacial Disorders; Ectodermal Dysplasias; Hearing Impairments FOLATE METABOLISM; INBORN ERROR OF See: Cobalamin (B12) Defiency FOOD ALLERGY See also: Asthma & Allergy The Food Allergy Network 10400 Eaton PI.
Only 10 to 15% of monostotic
cases involve the head and neck; the most frequently involved sites in this region are the maxilla and mandible.
fibrous dysplasia (ossifying fibroma) of the mastoid.