monosomy X

monosomy X

monosomy X

A synonym sometimes used for gonadal dysgenesis.
References in periodicals archive ?
ET) This poster presentation demonstrates that, given the complex presentations of pregnancies affected by monosomy X and the influence these complexities introduce into non-invasive prenatal testing, appropriate genetic counseling both before and after administration of this testing is important for women and their families considering non-invasive prenatal testing for sex chromosome analysis.
They suggested that even though PBC is not common in women with the monosomy X condition in Turner's syndrome, it may be that "autoimmune diseases require mutations in several genes in different chromosomes.
Natera, a leading innovator in reproductive and prenatal genetic testing, today announced that the company's non-invasive prenatal screening test, Panorama[TM], will launch on March 1 for the detection of trisomy 21 (Down syndrome), trisomy 18 (Edwards syndrome), trisomy 13 (Patau syndrome) and select sex chromosome abnormalities, such as monosomy X (Turner's syndrome).
In clinical validation studies, Panorama demonstrated a sensitivity of greater than 99% when detecting common chromosomal abnormalities such as trisomy 21, trisomy 18 and trisomy 13; and 92% when detecting monosomy X.
Panorama has been validated globally and is currently being evaluated in several other clinical trials for the detection of genetic disorders, including trisomy 21, trisomy 18, trisomy 13, monosomy X, XXY, XYY, XXX and triploidy.
First Non-Invasive Prenatal Alternative to Detect Monosomy X --
Verinata is launching the Monosomy X option, a test for Turner syndrome, as an optional addition to the verifi (TM) prenatal test.
We believe the verifi test with the Monosomy X option presents a safer, non-invasive alternative for the detection of Turner syndrome.
The study tested for trisomy 21 (Down syndrome), trisomy 18 (Edwards syndrome), trisomy 13 (Patau syndrome) and sex chromosome abnormalities, such as monosomy X (Turner's syndrome).
Natera's non-invasive prenatal test is currently being evaluated in multiple clinical trials for detection of multiple disorders, including trisomy 13, trisomy 18, trisomy 21, XXY, XYY, XXX and monosomy X.
In addition, the results show the ability to correctly classify cases of monosomy X (Turner syndrome) and shows promise for other sex chromosome abnormalities.
The test also detected monosomy X (Turner syndrome), mosaicism for T21, T18 and monosomy X, translocation trisomies, a single instance of each of trisomy 20 and trisomy 16, and several sex chromosome aneuploidies.