mononuclear (redirected from mononuclear phagocytes)

mononuclear /mono·nu·cle·ar/ (-noo´kle-er)

1. having but one nucleus.

2. a cell having a single nucleus, especially a monocyte of the blood or tissues.

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mon·o·nu·cle·ar (mn-nkl-r)

adj.

Having only one nucleus.

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mononuclear

having only one nucleus.

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blockade of mononuclear-phagocytic system

results when large numbers of particles or bacteria absorb all available receptor sites or otherwise interfere with phagocytosis. May be a factor in reducing host defense mechanisms.

mononuclear phagocytes

macrophages.

mononuclear phagocyte system

the group of highly phagocytic cells that have a common origin from stem cells of the bone marrow and develop circulating monocytes and tissue macrophages, which develop from monocytes that have migrated to connective tissue of the liver (Kupffer's cells), lung, spleen and lymph nodes. The term has been proposed to replace reticuloendothelial system, which includes some cells of different origin.