mononuclear


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mononuclear

 [mon″o-noo´kle-ar]
having only one nucleus.

mon·o·nu·cle·ar

(mon'ō-nū'klē-ăr),
Having only one nucleus; used especially in reference to phagocytic cells.

mononuclear

/mono·nu·cle·ar/ (-noo´kle-er)
1. having but one nucleus.
2. a cell having a single nucleus, especially a monocyte of the blood or tissues.

mononuclear

(mŏn′ō-no͞o′klē-ər, -nyo͞o′-)
adj.
1. Having only one nucleus: a mononuclear cell.
2. Chemistry Monocyclic.

mononuclear

[-nyo̅o̅′klē·ər]
Etymology: Gk, monos, single; L, nucleus, nut kernel
pertaining to one nucleus, such as a monocyte.

mon·o·nu·cle·ar

(mon'ō-nū'klē-ăr)
Having only one nucleus; used especially in reference to blood cells.

mononuclear

having only one nucleus.

blockade of mononuclear-phagocytic system
results when large numbers of particles or bacteria absorb all available receptor sites or otherwise interfere with phagocytosis. May be a factor in reducing host defense mechanisms.
mononuclear phagocytes
macrophages.
mononuclear phagocyte system
the group of highly phagocytic cells that have a common origin from stem cells of the bone marrow and develop circulating monocytes and tissue macrophages, which develop from monocytes that have migrated to connective tissue of the liver (Kupffer's cells), lung, spleen and lymph nodes. The term has been proposed to replace reticuloendothelial system, which includes some cells of different origin.
References in periodicals archive ?
Previous publications reported elevated levels of IL-22 mRNA in peripheral blood mononuclear cells from individuals with atopic that correlate with the severity of asthma [11-13].
The granuloma is a focal compact collection of inflammatory cells with predominance of mononuclear cells and is generally formed as a result of a persistence of some product non degradable with active hypersensitivity (7, 8).
CD 30 showed positive in all mononuclear cells (Figure 6) and CD 15 showed focal positivity in the mononuclear cells (Figure 7).
As we have shown previously in an acute perinatal cerebral hypoxic-ischemia model in newborn rats [8, 9], mononuclear cells derived from human cord blood show a highly specific "homing" and migrate into the lesioned region of the brain in large numbers within 24 hours when given intraperitoneally [9,10].
For phenotypic assay of mononuclear cells the antibodies were used according to a previous report for characterization of canine mesenchymal stem cells (JUNG et al.
Hepatitis C virus replicates in peripheral blood mononuclear cells of patients with occult hepatitis C virus infection.
The process of collecting, purifying and chemically tagging the patients' mononuclear cells is relatively expensive, complex and time consuming.
Enteroviruses cause modest CSF pleocytosis (50-400 WBC), usually with mononuclear predominance and relatively normal CSF chemistries.
The pathologic examination of the surgical specimen from neck dissection shows numerous multinucle ated osteoclast-like giant cells within cellular and vascular stroma containing plump, oval mononuclear cells with nuclei similar to giant cells (Figure 3); expansile and infiltrative growth; frequent mitotic figures; secondary cystic degeneration, reactive bone formation; no cytologic atypia or pleomorphism.
As for HCMV diagnostics, three methods were used: (i) ELISA, (ii) affinity and avidity of HCMV antibodies, and (iii) identification of HCMV genome by PCR method in blood plasma and mononuclear cells.