alveolar rhabdomyosarcoma

(redirected from monomorphous round cell rhabdomyosarcoma)
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alveolar rhabdomyosarcoma

An aggressive rhabdomyosarcoma that arises in the extremities, pelvis, and trunk of children to young adults (10 to 25).
DiffDx Ewing sarcoma, melanoma, neuroblastoma.
Prognosis Poor; metastasises to lungs and regional lymph nodes. Alveolar RMS’s bad behaviour (compared to embryonal RMS) is attributed to the t(2;13) translocation.