monoclonal


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Related to monoclonal: Monoclonal gammopathy, monoclonal immunoglobulin, monoclonal protein

monoclonal

 [mon″o-klo´nal]
derived from a single cell; pertaining to a single clone.

mon·o·clo·nal

(mon'ō-klō'năl),
In immunochemistry, pertaining to a protein from a single clone of cells, all molecules of which are the same; for example, in the case of Bence Jones protein, the chains are all κ or λ.

monoclonal

/mono·clo·nal/ (-klōn´al)
1. derived from a single cell.
2. pertaining to a single clone.

monoclonal

(mŏn′ə-klō′nəl)
adj.
Derived as clones from a single cell or produced by clones of a single cell: a monoclonal tumor.
n.
A monoclonal product, such as a monoclonal antibody.

monoclonal

[mon′əklō′nəl]
Etymology: Gk, monos + klon, twig
pertaining to or designating a group of identical cells or organisms derived from a single cell or organism. Compare polyclonal.

monoclonal

adjective Referring to a single clone of cells.

mon·o·clo·nal

(mon'ō-klōn'ăl)
immunochemistry Pertaining to a protein from a single clone of cells, all molecules of which are the same.

monoclonal

Of a group of cells derived from a single cell, all having the same GENOTYPE. Of a single CLONE of cells.

Monoclonal

Identical cells or proteins; cells (clones) derived from a single, genetically-distinct cell, or proteins produced by these cells.

monoclonal

derived from a single cell; pertaining to a single clone.

monoclonal antibodies
identical immunoglobulin molecules formed by a single clone of plasma cells; may occur naturally in plasma cell myelomas or in vitro by the fusion of an antibody producing B lymphocyte with a non-antibody-producing myeloma B cell. The fused heterokaryon has the properties of immortality and production of a monoclonal antibody. For the most part, monoclonal antibodies are made in mouse systems.
monoclonal gammopathy
see monoclonal gammopathy.
References in periodicals archive ?
Table 40: European Long-term Projections for Monoclonal Antibody Based Products by Geographic Region - France, Germany, Italy, UK & Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart) III-46
Cancer Monoclonal Antibody Partnering Agreements includes: Trends in cancer monoclonal antibody dealmaking in the biopharma industry since 2009 Analysis of cancer monoclonal antibody deal structure Access to headline, upfront, milestone and royalty data Access to over 300 cancer monoclonal antibody deal records The leading cancer monoclonal antibody deals by value since 2009
Increased competition for antibody targets and patient populations, pricing pressures from governments and other healthcare payers, patent expiry for high-revenue monoclonal antibodies and the spectre of biosimilar monoclonal antibodies will come to the fore during the period 2009 to 2024.
2 Overview of Global Monoclonal Antibody Industry 2.
The period 2009 to 2019 will reveal volatility in the monoclonal antibody therapies market as current-leading products reach peak sales and new-generation drugs emerge.
This report contains over 250 links to online copies of actual cancer monoclonal antibody deals and where available, contract documents as submitted to the Securities Exchange Commission by companies and their partners.
Herold's team ultimately treated 42 people, half of whom received monoclonal antibodies.
Our US partner is providing us with a monoclonal antibody for a first phase proof of principle project.
Monoclonal Antibodies Phase 2 Clinical Trial Pipeline Insights
India, Europe and Australia have been proposed as major market where biosimilar breast cancer monoclonal antibodies would be marketed in incipient stages.
4 Reagent monoclonal anti-B, the first clone and two different series of one clone.