monoclonal

monoclonal /mono·clo·nal/ (-klōn´al)

1. derived from a single cell.

2. pertaining to a single clone.

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mon·o·clo·nal (mn-klnl)

n.

Of or relating to a protein from a single clone of cells, all molecules of which are the same, as in the Bence-Jones protein.

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Monoclonal

Identical cells or proteins; cells (clones) derived from a single, genetically-distinct cell, or proteins produced by these cells.

Mentioned in: Alemtuzumab, Multiple Myeloma, Waldenström's Macroglobulinemia

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monoclonal

[mon′əklō′nəl]

Etymology: Gk, monos + klon, twig

pertaining to or designating a group of identical cells or organisms derived from a single cell or organism. Compare polyclonal.

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monoclonal

derived from a single cell; pertaining to a single clone.

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monoclonal antibodies

identical immunoglobulin molecules formed by a single clone of plasma cells; may occur naturally in plasma cell myelomas or in vitro by the fusion of an antibody producing B lymphocyte with a non-antibody-producing myeloma B cell. The fused heterokaryon has the properties of immortality and production of a monoclonal antibody. For the most part, monoclonal antibodies are made in mouse systems.

monoclonal gammopathy

see monoclonal gammopathy.