monoblastic leukemia


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Related to monoblastic leukemia: monocytic leukaemia

monoblastic leukemia

[-blas′tik]
a malignancy of blood-forming organs, characterized by the proliferation of monoblasts and monocytes. The disease develops late in the course of a small but significant number of cases of plasma cell myeloma. Also called monocytic leukemia, Schilling's leukemia.

mon·o·cyt·ic leu·ke·mi·a

(mon'ō-sit'ik lū-kē'mē-ă)
A form of leukemia characterized by large numbers of cells that can be definitely identified as monocytes, in addition to larger, apparently related cells formed from the uncontrolled proliferation of the reticuloendothelial tissue. The disease runs an acute or subacute course in older people, and is characterized by swelling of gums, oral ulceration, bleeding in skin or mucous membranes, secondary infection, and splenomegaly.