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monobactam

   Also found in: Wikipedia 0.01 sec.
monobactam /mon·o·bac·tam/ (-bak´tam)
1. a class of synthetic antibiotics with a cyclic beta-lactam nucleus.
2. a class of synthetic antibiotics having a monocyclic β nucleus.

monobactam
a group of monocyclic β-lactamase resistant antibiotics which includes aztreonam and carumonam sodium.


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These molecules have versatile hydrolytic capacities that inactivate antibiotics in the penicillin, cephalosporin, monobactam, and carbapenem families.
These B-lactams antibiotics are a broad class of the most widely used antibiotics which include penicillin, cephalosporin, monobactam and carbapenem to name but a few.
Imipenem (a carbapenem) not only failed to induce expression but also inhibited induction by the adjacent monobactam, aztreonam (not shown), at subgrowth-inhibitory levels.
 
 
 
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