monoaminoxidase

monoaminoxidase

an enzyme that inactivates NORADRENALINE by oxidation in ADRENERGIC nerves.
Mentioned in ?
References in periodicals archive ?
The action of serotonin (5-hydroxytryptamine 5-HT) in the synapse is terminated by monoaminoxidase enzyme activity and neuronal uptake pump for 5-HT which allows reuse of the 5-HT molecules in the presynaptic neuron.
Desde a decada de 1950, com a descoberta da acao terapeutica dos antidepressivos triciclicos (ADTs) e dos inibidores da monoaminoxidase (IMAOs), diversos grupos de farmacos foram acrescentados ao arsenal terapeutico, tais como os inibidores seletivos da recaptacao da serotonina (ISRSs), os inibidores da recaptacao de serotonina e noradrenalina (IRSNs), o antagonista noradrenergico e serotoninergico especifico (mirtazapina), os antagonistas 5-HT2, a bupropiona e, mais recentemente, a agomelatina (Sena, 2009).
In general, monoaminoxidase inhibitors (MAOi), tricycles or SSRIs may induce suppression on reproductive axis (LABBATE et al.
In this there are biological causes (higher testosterone levels, lower levels of monoaminoxidase and cortical immaturity during puberty and adolescence in males) and socio-cultural determinants (gender role regardless of alexithymia, or difficulty to verbally identify and express emotions) (Moral, 2010a).
Para o controle farmacologico da depressao sao disponibilizados os Antidepressivos Triciclicos (ATCs) tendo como exemplo a imipramina, doxepina, protriptilina e amitriptilina; Antidepressivos de Segunda Geracao (ASG) exemplificados pela amoxapina, maprotilina, trazodona e a bupropiona; Antidepressivos de Terceira geracao (ATG) como a mirtazapina, venlafaxina, nefazodona, duloxetina; Inibidores Seletivos da Recaptacao de Serotonina (ISRS) que incluem a fluoxetina, paroxetina, sertralina, fluvoxamina e o citalopram; os Inibidores da Monoaminoxidase (IMAO) que sao representados pela fenelzina, isocarboxazida e a tranilcipromina (Katzung, 2010).
In these glands, monoaminoxidase, the enzyme that metabolizes 5-HT is also detected.
In addition, the drink contains a monoaminoxidase (MAO) inhibitor from the vine Banisteriopsis caapi.
Os antidepressivos triciclicos, os inibidores da monoaminoxidase (IMAO) e os inibidores seletivos da recaptacao de serotonina (ISRS) foram os agentes avaliados.
Although some clinical and experimental studies suggest it has some properties similar to conventional antidepressants, the proposed mechanism of action seems to be multiple: a non-selective blockade of the reuptake of serotonin, noradrenaline and dopamine; an increase in density of serotonergic and dopaminergic receptors and an increased affinity for GABAergic receptors; moreover, the inhibition of monoaminoxidase enzyme activity has been involved.
clomipramine, imipramine and desipramine), monoaminoxidase inhibitors (i.
44] More recently, apomorphine has been shown to significantly limit 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine (MPTP)-induced nigrostriatal dopaminergic cell loss in vivo in mice and to inhibit mice striatal monoaminoxidase A and B activities in vitro.
Somente duas classes de antidepressivos eram conhecidas ate a decada de 80, os triciclicos e os inibidores de monoaminoxidase.