monoamine

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monoamine

 [mon″o-am´ēn]
an amine containing only one amino group.
monoamine oxidase (MAO) a copper-containing enzyme that deaminates monoamines such as dopamine, epinephrine, norepinephrine, and serotonin. See also monoamine oxidase inhibitor.

mon·o·am·ine

(mon'ō-am'ēn, -in), Although this word is correctly stressed on the second-last syllable, U.S. usage often stresses it on the last syllable.
A molecule containing one amine group.
Synonym(s): monamine

monoamine

/mono·amine/ (mon″o-ah-mēn´) an amine containing one amino group, e.g., serotonin, dopamine, epinephrine, and norepinephrine.

monoamine

(mŏn′ō-ăm′ēn, -ə-mēn′)
n.
An amine compound containing one amino group, especially a compound that functions as a neurotransmitter.

monoamine

[mon′ō·am′in]
an amine containing one amine group.

monoamine

A class of molecules that contain one amino group connected to an aromatic ring by a two-carbon chain. The physiologically important monoamines derive from aromatic amino acids—phenylalanine, tyrosine, tryptophan—and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes. They include neurotransmitters and neuromodulators, in particular catecholamines (dopamine, epinephrine and norepinephrine) and tryptamines (serotonin and melatonin).

monoamine

Pharmacology A class of hormones or neurotransmitters–eg, catecholamines–dopamine, epinephrine, norepinephrine and indoleamines–serotonin, melatonin, which have 1 amine. See Catecholamine.

mon·o·am·ine

, monamine (mon'ō-ǎ-mēn', mon-amin)
A molecule containing one amine group.

monoamine

an amine containing only one amino group.

monoamine oxidase
a cuproprotein enzyme that deaminates monoamines such as serotonin, epinephrine, norepinephrine, dopamine, tyramine and tryptamine. Called also MAO.
monoamine oxidase inhibitors
substances that inhibit the activity of monoamine oxidase, increasing catecholamine and serotonin levels in the brain; they are used as antidepressants and antihypertensives. Called also MAO inhibitors.
References in periodicals archive ?
16) Unlike the dextro isomers, L-amphetamine structures do not inhibit dopamine reuptake or cause euphoria, but can cause stimulation (eg, sleep disturbance) by inhibiting norepinephrine reuptake, and also by interacting with the trace amine-associated receptor 1 (TAAR1), an intracellular receptor expressed within the presynaptic terminal of monoamine neurons.
Phenylalanine plays a significant role in the synthesis and regulation of monoamine neurotransmitters.
Current antidepressant drug therapies include selective serotonin reuptake inhibitors, serotonin and noradrenaline reuptake inhibitors and the older, less specific monoamine regulating drugs.
A single dose of VW was selected for the estimation of brain monoamines, which was most appropriate according to the effects of VW on sleep architecture (200 mg/kg body weight).
Attempts can be made to either lower elevated levels of MAO-A with selected antagonist drugs, or to increase the concentration of monoamine neurotransmitters that can elevate mood.
Measurement of monoamine metabolites in CSF can therefore be used to establish a "snapshot" of serotonin and catecholamine metabolism at one particular time that may provide an indication of disease mechanisms that affect the neurotransmitter pathways.
For this purpose, we evaluated locomotor activity across the course of exposure, whereas monoamine levels in striatum, prefrontal cortex, nucleus accumbens, and hypothalamus and stereologic cell counts of TH-positive (T[H.
Pharmacologic treatments for depression have advanced greatly since the development of the first therapies, monoamine oxidase inhibitors (MAOIs).
Exposure to styrene in rats produced a significant increase in brain 5-HT and caused a significant decrease in monoamine oxidase (MAO) activity (Husain, Srivastava, Mushtaq, & Seth, 1980).
I argue that one approach to answering this question consists of investigating the nature of such purported theories and I focus on the monoamine hypothesis of clinical depression.
We also observed decreases in cerebral cortex monoamines levels, as well as plasma CORT level in stressed mice.