Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic
neuronal phenotypes in the vertebrate hindbrain.
In utero exposure to a low concentration of diesel exhaust affects spontaneous locomotor activity and monoaminergic
system in male mice.
Ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, has been shown to potentiate the effects of other analgesics, such as morphine, by reducing the development of tolerance to such opioids and by directing the analgesic actions of ketamine via monoaminergic
, cholinergic and mu mechanisms.
A number of dysregulated biological pathways have been identified in major depressive disorder (MDD) including disturbances in monoaminergic
activity, immuno-inflammation, oxidative stress, hypothalamus-pituitaryadrenal (HPA) activity and neuroprogression.
Anti-depressant-like effect of vitexin in BALB/c mice and evidence for the involvement of monoaminergic
The neuropsychopharmacology of fronto-executive function: monoaminergic
Despite equivocal data, there seems to be an increase in [alpha]2-adrenergic receptors supporting the monoaminergic
reduction theory of depression and suicide.
Dissociable deficits in the decision-making cognition of chronic amphetamine abusers, opiate abusers, patients with focal damage to prefrontal cortex, and tryptophan-depleted normal volunteers: Evidence for monoaminergic
Spanning more than a decade, a plethora of candidate gene studies investigated targets related to the monoaminergic
hypothesis of antidepressant effect, and serotonergic neurotransmission in particular.
at 604 ("Research documenting serotonin (5-hydroxyindoleacetic acid; 5-HT) deficiencies among individuals with antisocial, aggressive, and impulsive behavior (Carver & Miller, 2006) suggests that genes that code for proteins important for monoaminergic
neurotransmission influence psychopathy.
The combination of MAO inhibitors such as some ayahuasca j carbolines with monoaminergic
and serotoninergic substances in general, antidepressives, as well as ginseng, St John's wort, dextromethorphan, amphetamine, and 3,4-methylenedioxymethamphetamine (MDMA: "ecstasy"), could produce the serotonin syndrome (dos Santos 2013a; Pilgrim et al.
One option might be to start patients getting a single ketamine dose on an approved monoaminergic
antidepressant or mood stabilizer, Dr.