monoamine


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monoamine

 [mon″o-am´ēn]
an amine containing only one amino group.
monoamine oxidase (MAO) a copper-containing enzyme that deaminates monoamines such as dopamine, epinephrine, norepinephrine, and serotonin. See also monoamine oxidase inhibitor.

mon·o·am·ine

(mon'ō-am'ēn, -in), Although this word is correctly stressed on the second-last syllable, U.S. usage often stresses it on the last syllable.
A molecule containing one amine group.
Synonym(s): monamine

monoamine

/mono·amine/ (mon″o-ah-mēn´) an amine containing one amino group, e.g., serotonin, dopamine, epinephrine, and norepinephrine.

monoamine

(mŏn′ō-ăm′ēn, -ə-mēn′)
n.
An amine compound containing one amino group, especially a compound that functions as a neurotransmitter.

monoamine

[mon′ō·am′in]
an amine containing one amine group.

monoamine

A class of molecules that contain one amino group connected to an aromatic ring by a two-carbon chain. The physiologically important monoamines derive from aromatic amino acids—phenylalanine, tyrosine, tryptophan—and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes. They include neurotransmitters and neuromodulators, in particular catecholamines (dopamine, epinephrine and norepinephrine) and tryptamines (serotonin and melatonin).

monoamine

Pharmacology A class of hormones or neurotransmitters–eg, catecholamines–dopamine, epinephrine, norepinephrine and indoleamines–serotonin, melatonin, which have 1 amine. See Catecholamine.

mon·o·am·ine

, monamine (mon'ō-ǎ-mēn', mon-amin)
A molecule containing one amine group.

monoamine

an amine containing only one amino group.

monoamine oxidase
a cuproprotein enzyme that deaminates monoamines such as serotonin, epinephrine, norepinephrine, dopamine, tyramine and tryptamine. Called also MAO.
monoamine oxidase inhibitors
substances that inhibit the activity of monoamine oxidase, increasing catecholamine and serotonin levels in the brain; they are used as antidepressants and antihypertensives. Called also MAO inhibitors.
References in periodicals archive ?
Interestingly, some of these symptoms are reversed after administration of a monoamine oxidase inhibitor--an antidepressant medication that reduces the degradation of dopamine (Kato, Iwata, Okamoto, Ishii, & Narita, 2000).
Maruyama, "Modulation of monoamine oxidase (MAO) expression in neuropsychiatric disorders: genetic and environmental factors involved in type A MAO expression," Journal of Neural Transmission, vol.
Structures of glicoricone and licofuranone, and inhibitory effects of licorice constituents on monoamine oxidase.
The two key neurotransmitters implicated in the monoamine hypothesis are noradrenaline and serotonin.
Measurement of monoamine metabolites in CSF can therefore be used to establish a "snapshot" of serotonin and catecholamine metabolism at one particular time that may provide an indication of disease mechanisms that affect the neurotransmitter pathways.
1998) and is an inhibitor of monoamine oxidase B that activates MPTP neuorotoxicity (Yong and Perry 1986).
Criminal violence, for example, might be excused as a consequence of low levels of serotonin or monoamine oxidase in the brain.
The paint contains an ingredient with marine biocide properties, wherein the binder comprises a blend of the rosin material and an auxiliary film-forming resin in a ratio of 20:80 to 95:5 by weight, the auxiliary film-forming resin comprising 20-100% by weight of an acid-functional film-forming polymer whose acid groups are blocked by groups capable of hydrolyzing or dissociating to leave a polymer soluble in sea water, the blocking groups being selected from divalent metal atoms bonded to a monovalent organic residue, divalent metal atoms bonded to a hydroxyl residue and monoamine groups which form an organic solvent soluble amine salt of the polymer, and 80% to zero percent by weight of a non-hydrolyzing water-insoluble film-forming polymer.
Exposure to styrene in rats produced a significant increase in brain 5-HT and caused a significant decrease in monoamine oxidase (MAO) activity (Husain, Srivastava, Mushtaq, & Seth, 1980).
Furthermore, review articles tell of rats trained to run spontaneously that showed an increase both in beta-endorphin and in monoamine concentration in their cerebrospinal fluid (1, 9).