ABX-1431 is a novel small molecule that modulates the levels of an endogenous cannabinoid, 2-arachidonoylglycerol (2-AG), through inhibition of monoacylglycerol lipase
Lipolysis in adipocytes is regulated in a step-wise fashion by adipose triglyceride lipase (ATGL), hormone-sensitive lipase (HSL), and monoacylglycerol lipase
Washington, November 2 ( ANI ): A new study has identified an enzyme called Monoacylglycerol lipase
(MAGL) as a potential therapeutic target to treat or prevent Alzheimer's disease.
Under the three-year agreement, Abide and Oxford will explore the role of monoacylglycerol lipase
(MGLL) inhibitors in altering endocannabinoid tone in the human brain.
Experts at The Scripps Research Institute identified the enzyme, called monoacylglycerol lipase
(MAGL) as a key player responsible for the aggressive behaviour of cancer cells.
Pioneering innovative approaches to selectively target the serine hydrolase enzymes group with collaborators at UC San Diego, Abide has created novel small molecule inhibitors of its target enzyme, monoacylglycerol lipase
(MAGL) of the serine hydrolase family through the company's selective targeting technology.
The enzymes that synthesize and degrade the endocannabinoids, such as fatty acid amide hydrolase or monoacylglycerol lipase