mithramycin

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plicamycin

 [pli″kah-mi´sin]
an antineoplastic antibiotic produced by Streptomyces plicatus that binds to DNA and inhibits RNA synthesis; it is used for treatment of advanced testicular carcinoma; major side effects are thrombocytopenia and hemorrhagic diathesis that can be life-threatening. It also has an inhibiting effect on osteoclasts and is used to treat hypercalcemia and hypercalciuria caused by metastatic malignancy. Administered intravenously. Formerly called mithramycin.

mith·ra·my·cin

(mith'ră-mī'sin),
An antibiotic produced by Streptomyces argillaceus and S. tanashiensis; possesses antineoplastic activity.

mithramycin

/mith·ra·my·cin/ (mith″rah-mi´sin) plicamycin.

mithramycin

mithramycin

A drug that reduces bone metabolism and can be useful in the treatment of PAGET'S DISEASE and HYPERCALCAEMIA.

mith·ra·my·cin

(mith'ră-mī'sin)
An antibiotic produced by Streptomyces argillaceus and S. tanashiensis; possesses antineoplastic activity.

mithramycin