mitotic index


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mi·tot·ic in·dex

the ratio of cells in a tissue that are undergoing mitosis, often expressed as either the number of cells in a specified area of tissue section or as a percentage of the total cell sample.

mitotic index

the number of cells per unit (usually 1000 cells) undergoing mitosis during a given time. The ratio is used primarily as an estimation of the rate of tissue growth.

mitotic index

The percentage of cells in a population that are actually undergoing MITOSIS. The mitotic index is a measure of the reproductive or growth activity of a tissue.

mitotic index

(mītot´ik),
n the number of cells per unit undergoing mitosis during a given time. The ratio is used primarily as an estimation of the rate of tissue growth.

mitotic

pertaining to mitosis.

mitotic activity
degree to which a cell population is proliferating; used as an index of tumor aggression. Can be quantified by counting the percentage of cells showing mitotic figures, or by flow cytometry.
mitotic figure
the condensed chromosomes by which a cell that is undergoing mitosis can be identified.
mitotic index
the percentage of cells simultaneously in the process of division, normally calculated after counting 1000 cells. Used in morbid pathology as a measure of the malignancy of a tumor, and in clinical pathology as an index of survival time of a neoplasm.
mitotic metaphase chromosomes
chromosomes in metaphase manifesting as mitotic figures.
mitotic nondisjunction
failure of proper disjunction of the paired chromosomes during metaphase which results in the chromosomal abnormalities of monosomy or trisomy.
mitotic potential
estimate of the cell's potential reproductive capacity.
References in periodicals archive ?
The highest value of mitotic index belonged to dry and wet pretreated seeds with 60 minutes exposure time.
The mitotic index and PCNA index increased significantly in regenerating liver of rats of Group III over the Group II at the 72nd hour of post partial hepatectomy.
90 Table 2: Effec of oily sludge on Allium cepa--24 hrs treatment percentage of abnormalities and mitotic index.
Fluoxymesterone neither induced chromosomal aberrations (Table 1 and 2) and sister chromatid exchanges (Table 4) nor affected mitotic index (Table 1 and 2) and replication index (Table 4) at significant level even at the highest tested dose i.
The launch of our PathHunter Mitotic Index assays is a major step toward attaining simple, powerful, yet generic cell based assays that accelerate the drug discovery process," said Pyare Khanna, CEO of DiscoveRx Corp.
The mitotic index of the high-resolution cultures was lower than that of the standard cultures for all groups.
The mitotic index was variable, with up to 30 mitotic figures per 10 high-powered fields.
These changes were largely based on several reports by Perry and colleagues, (9,10) in which the relationship between pathologic subtype, mitotic index, invasive capacity, and other microscopic factors was correlated with tumor recurrence.
Guidelines for Risk Assessment of Primary Gastrointestinal Stromal Tumor (a) Tumor Parameters Mitotic Index Size, cm [less than or equal to] [less than or equal to] 2 5 per 50 HPFs >2 but [less than or equal to] 5 >5 but [less than or equal to] 10 >10 >5 per 50 HPFs [less than or equal to] 2 >2 but [less than or equal to] 5 >5 but [less than or equal to] 10 >10 Tumor Parameters Risk of Progressive Disease (b) (%) Mitotic Index Stomach Duodenum [less than or equal to] None (0) None (0) 5 per 50 HPFs Very low (1.
Proposed Risk Assessment Scheme for Predicting Aggressive Clinical Behavior in Gastrointestinal Stromal Tumors According to Mitotic Index, Size, and Site (a) Risk for Progressive Disease (b) (%) Mitotic Index, HPF Size, cm Gastric [less than or [less than or None (0) equal to] 5/50 equal to] 2 [less than or >2, [less than Very low (1.
We will refer to the mean mitotic count per 10 HPFs when 1 or more sets of 10 HPFs are counted as the mitotic index (MI).
The mitotic index should be reported as the number of mitoses per square millimeter.