mitomycin C

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mitomycin, mitomycin C

a group of highly toxic antineoplastics (mitomycin A, B and C) produced by Streptomyces caespitosus, indicated for palliative treatment of certain neoplasms that do not respond to surgery, radiation and other drugs.
References in periodicals archive ?
32]P-Analysis if DNA adducts in somatic and reproductive tissues of rats treated with the anticancer antibiotic, mitomycin C.
Nucleotide excision repair- and polymerase [eta]-mediated error-prone removal of mitomycin c interstrand cross-links.
In previously published studies, the concentration of mitomycin C solution varied from 0.
In 1999, Yazawa et al published their experience with mitomycin C during endolymphatic sac surgery, and they reported no heating impairment or dizziness among 14 patients who had been followed for more than 6 months.
In conclusion, our study of a limited number of ears showed that a conservative surgical approach combined with topical application of mitomycin C can be a safe and successful method of treating fibrous atresia of the external auditory canal.
Effect of brief exposure to mitomycin C on viability and proliferation of cultured human Tenon's capsule fibroblasts.
Effects of 5-fluorouracil and mitomycin C on cultured rabbit subconjunctival fibroblasts.
O'Reilly RC, Goldman SA, Widner SA, Cass SE Creating a stable tympanic membrane perforation using mitomycin C.
Use of mitomycin C for maintaining myringotomy patency.
Intraoperative mitomycin C in endolymphatic sac surgery for Meniere's disease: A pilot study.
Contact diode laser myringotomy and mitomycin C in children.