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mitogen
(redirected from mitogenicity)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
mitogen /mi·to·gen/ (mīt″o-jen) a substance that induces mitosis and cell tranformation, especially lymphocyte transformation.mitogen´ic
mi·to·gen (mt-jn)
n.
An agent that stimulates mitosis and lymphocyte transformation.

mito·genic (mt-jnk, mt-) adj.
mito·ge·nici·ty (-j-ns-t) n.

mitogen
[mī′təjən, mit′-]
Etymology: Gk, mitos + genein, to produce
an agent that triggers mitosis. mitogenic, adj.

mitogen [mi´to-jen]
a substance that induces blast transformation; DNA, RNA, and protein synthesis; and proliferation of lymphocytes; e.g., concanavalin A, phytohemagglutinin, or lipopolysaccharide.

mitogen,
n an agent that triggers mitosis.

mitogen
an agent that induces mitosis and lymphocyte blastogenesis.

pokeweed mitogen (PWM)
a lectin from the plant, Phytolacca americana, that produces B and T lymphocyte blastogenesis.


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3)-[beta]-D-glucans, have demonstrated mitogenicity and activation of immune effector cells (Smith 2002, Zhou 2002) as well as a stimulating effect on the production of cytokines (Smith 2002, Goa 2004).
Some of the biologic responses associated with cellular reactions to endotoxin include fever induction, macrophage activation, B-cell mitogenicity, restrictive lung function changes, and reduction in alveolocapillary gas transfer (Cotran, Kumar, & Collins, 1999; Rylander, 1997).
[FIGURE 4 OMITTED] Addition of serum 96/2-4 or 96/2-10 selectively increased the mitogenicity of SPE-J by twofold compared to the FCS control.
 
 
 
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