mitogen-activated protein kinase

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Related to mitogen-activated protein kinase: MAP kinase, MAPK

MAP kinase

Any of a family of serine/threonine protein kinases belonging to the CMGC (CDK/MAPK/GSK3/CLK) kinase group, which are involved in cellular responses to various stimuli (e.g., mitogens, osmotic stress, heat shock and cytokines) and regulate cell growth, cycling, differentiation, mitosis and apoptosis.

mitogen-activated protein kinase



A signaling protein, i.e., a protein that circulates extracellularly influencing other cells to turn on the process of protein synthesis. These proteins have an effect on cellular replication and cellular death in inflammatory, ischemic, and malignant diseases.

mitogen-activated protein kinase

Abbreviation: MAPK
A signaling enzyme, i.e., one that circulates extracellularly, influencing cells to begin protein manufacturing. They affect cellular replication and death in inflammatory, ischemic, and malignant diseases.
See also: protein kinase
References in periodicals archive ?
MEKK1, mitogen-activated protein kinase kinase kinase 1; PKC, protein kinase C; NIK, NF-[kappa]B inducing kinase; NEDD8, neural precursor cell expressed developmentally downregulated 8.
Sodium antimony gluconate induces generation of reactive oxygen species and nitric oxide via phosphoinositide 3-kinaseand mitogen-activated protein kinase activation in Leishmania donouani-infected macrophages.
TNF-[alpha] induction by Pseudomonas aeruginosa lipopolysaccharide or slime-glycolipoprotein in human monocytes is regulated at the level of Mitogen-activated Protein Kinase activity: a distinct role of Toll-like receptor 2 and 4.
Interpretation & conclusions: The ex vivo expansion of human limbal epithelial progenitor cells on intact HAM was mediated by PI3K/Akt/FKHRLI pathway, which is known to govern cell survival, and the mitogen-activated protein kinase (MAPK) pathway, known to control the cell mitosis.
Goldstone SD, Hunt NH: Redox regulation of the mitogen-activated protein kinase pathway during lymphocyte activation.
Also known as HER2/Neu ERK Extracellular signal-regulated Kinases Ile amino acid isoleucine MEK Mitogen-activated protein kinase kinase NCBI National Center for Biotechnology Information PSI-BLAST Position-Specific Iterative BLAST Val amino acid Valine Table 2.
The findings in this report could be attributable to a nongenomic action of the supraphysiological peak L-thyroxine concentrations on the parathyroid cells, possibly via mitogen-activated protein kinase, bypassing the calcium-sensing receptor regulation (4).
Mitogen-activated protein kinase (MAP-kinase) is a protein that carries out Ras functions.
Mitogen-activated protein kinase in neutrophils and enucleate neutrophil cytoplasts: evidence for regulation of cell-cell adhesion.
Phosphorylation of mitogen-activated protein kinase by one-trial, and multi-trial classical conditioning.

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