mitochondrial ribosome

mitochondrial ribosome

An intracellular structure responsible for the biosynthesis of protein components that are crucial to the generation of ATP in eukaryotic cells. Mitochondrial ribosomes resemble prokaryotic ribosomes, rather than the cytoplasmic ribosomes of the cells containing the mitochondria. The mitochondrial ribosome possesses intersubunit bridges composed largely of proteins; it has a gatelike structure at its mRNA entrance, and may be involved in recruiting unique mitochondrial mRNAs. It also has a polypeptide exit tunnel that allows access to the solvent before the exit site, suggesting a unique nascent-polypeptide exit mechanism.
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29) Based on the first theory, mRNA translation may be utilized by extra mitochondrial ribosomes and the second theory states that mRNA translation may be performed by intra mitochondrial ribosomes.
Additionally, Schimmer believes it's possible that chemists could design tigecycline analogues that would be more potent or more selective of mitochondrial ribosomes over bacterial ones.
1971), and those inhibited by chloramphenicol (CAP), which inhibits protein synthesis on 70S plastid and mitochondrial ribosomes (Lamb et at.
1] in absolute ethanol) was used to inhibit translation on 70S plastid and mitochondrial ribosomes.
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