mitochondrial respiration


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Related to mitochondrial respiration: cellular respiration, Cell respiration

mitochondrial respiration

The stages of cell respiration (citric acid cycle and cytochrome transport system) that take place in the mitochondria. Water is formed from oxygen and hydrogen ions, and energy is released. See: cell respiration
See also: respiration
References in periodicals archive ?
Impaired mitochondrial respiration and protein nitration in the rat hippocampus after acute inhalation of combustion smoke.
Some allelopathic compounds are thought to interact with the mitochondrial membrane and to impair mitochondrial respiration directly.
With these two modifications, a broad spectrum of RNAs were targeted to and imported into the mitochondria, where they functioned to repair defects in mitochondrial respiration and energy production in two different cell line models of human mitochondrial disease.
In muscle, resveratrol activated AMPK, increased STRT1 and PGC-1[alpha] protein levels, increased citrate synthase activity without change in mitochondrial content, and improved muscle mitochondrial respiration on a fatty acid-derived substrate.
Indeed it is possible to induce this experimentally in isolated mitochondria, and is known as state 4 mitochondrial respiration (56).
Because mitochondrial respiration plays a critical role in glucose metabolism, mitochondrial dysfunction likewise has been shown to be associated with these conditions.
The MEGS capacity can be examined in detail by measurement of 14CO2 production rates from oxidation of [1-14C]pyruvate and carboxyl14C-labeled TCA cycle intermediates in combination with measurement of ATP production in intact mitochondria from a muscle biopsy (1), or by examining mitochondrial respiration via oxygen consumption measurements using polarography.
Previous animal studies suggested that a reduction in mitochondrial respiration could mimic a process called ischemic preconditioning, in which brief episodes of ischemia - a reduction in blood flow - actually protect tissue against being damaged if its blood supply is later cut off completely.
The primary factor regulating mitochondrial respiration when oxygen and fuel substrate availability are not limiting factors, is the concentration of ADP (18) or as noted by others, the [ATP]/[ADP]x[Pi] ratio (cellular energy state) (19).
Another mechanism of GBE action is the stabilization of mitochondrial respiration.
The study also confirmed that [DELTA]mtDNA affected mitochondrial respiration chain function and resulted in oligozoospermia, asthenozoospermia and teratozoospermia leading to infertility in mice.

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