miotics


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Related to miotics: glaucoma

miotics

Drugs that constrict the pupil. They may be used in the treatment of glaucoma and accommodative esotropia and, sometimes, after a mydriatic examination. Miotics are either parasympathomimetic (cholinergic-stimulating) drugs which have a direct muscarinic action, such as pilocarpine and carbachol, or anticholinesterase drugs which block the effect of acetylcholinesterase thus letting acetylcholine produce its effect, such as physostigmine, neostigmine, echothiophate and demecarium. There are also some miotics which act by blocking α-or β-adrenergic receptors. For example, dapiprazole and thymoxamine block the α-adrenergic receptors and propranolol blocks the β-adrenergic receptors. See adrenergic receptors; open-angle glaucoma; sphincter pupillae muscle; mydriatic; parasympathomimetic drug.
References in periodicals archive ?
58) The use of miotic drugs during pregnancy appears to be safe.
Prolonged use of long-acting miotics may be associated with usually bilateral, small, multiple cysts located along the papillary border.
The drugs that can be used by AS optometrists are linked to an approved formulary and include some topical antibiotics, lubricants, mast-cell stabilisers, anti-histamines, one non-steroidal anti-inflammatory as well as miotics and mydriatics (see www.
mt-1 variant are likely to show resistance to intraocular pressure lowering with traditional IOP-lowering agents such as beta-blockers and miotics.