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(neg'ă-tiv), Avoid the jargonistic use of this word as a synonym of normal or in expressions that may be obscure or ambiguous, as in negative findings and negative results.
1. Not affirmative; refutative; not positive; not abnormal.
2. Denoting failure of response, absence of a reaction, or absence of an entity or condition in question.
[L. negativus, fr. nego, to deny]


/neg·a·tive/ (neg´ah-tiv)
1. having a value less than zero.
2. indicating absence, as of a condition or organism.
3. characterized by refusal, denial, resistance, or opposition.


1. Marked by failure of response or absence of a reaction.
2. Not indicating the presence of a particular disease, condition, or organism.
3. Moving or turning away from a stimulus, such as light.

negative (neg)

Etymology: L, negare, to deny
1 (of a laboratory test) indicating that a substance or a reaction is not present.
2 (of a sign) indicating on physical examination that a finding is not present, often meaning that there is no pathological change.
3 (of a substance) tending to carry or carrying a negative chemical charge.


Lab medicine
noun A lab result that is normal; failure to show a positive result for the specific disease or condition for which the test is being done.

Vox populi
noun Absence or nonexistence of a thing or activity.


noun Lab medicine A lab result that is normal; failure to show a positive result for the specific disease or condition for which the test is being done. See False negative, Hemoccult negative, True negative Vox populi Absence or nonexistence of a thing.


1. Not affirmative; refutative; not positive.
2. mathematics Having a value less than zero.
3. physics, chemistry Having an electric charge resulting from a gain or overabundance of electrons, hence able to donate (lose) electrons.
4. medicine Denoting a response to a diagnostic maneuver or laboratory study that indicates the absence of the disease or condition tested for.
[L. negativus, fr. nego, to deny]


Not affirmative; refutative; not positive.
[L. negativus, fr. nego, to deny]


1. having a value of less than zero.
2. indicating lack or absence, as coagulase-negative or Brucella-negative.
3. characterized by denial or opposition.

negative feedback
negative reinforcement
in animal psychology the stimuli which produce withdrawal, immobility, aversion, escape.

Patient discussion about negative

Q. is her2 positive more agressive than her2 negative? i know someone with her2 positive breast cancer and her doctor said it was more difficult to detect upon its return if it came back i want to know if it is true and what can she do to detect it earlier

A. Over-expression of her2/neu, a specific molecule in the breast cancer cell is indeed considered to convey worse prognosis, and suggest the need for chemotherapy and immunotherapy with Herceptin. However, the decision is much more complicated and should be made on case by case basis after consulting a professional.

Q. Rising PSA to 10 with two negative biospies? Expect cancer? 67 yrs old in good health otherwise.

A. High values don't always mean it's cancer. At 67 years old, you're prostate is most likely enlarging, resulting in the higher PSA results. And after two negative biopsies, it sounds like you're in the clear. Like Brandon said though, keep up with your regular check ups.

Q. Does the cooking have a negative effect on the protein content of the food? I have heard that high temperatures cooking breaks the protein, so does the cooking have a negative effect on the protein content of the food?

A. Yes. Proteins can be denatured by heat, but only when the protein structure is delicate or is exposed to extremely high temperatures for long time. You must remember that breaking of protein is the physical-chemical process where the physical or chemical structure of a protein is rearranged. So cooking will not reduce on the nutritive value of the food until it’s cooked at cooking temperatures.

More discussions about negative
References in periodicals archive ?
The Supreme Court maintained its good net score but declined by two points, from +34 (57 percent satisfied minus 34 percent dissatisfied, rounded off) in the first quarter to +32 (53 percent satisfied minus 22 percent dissatisfied, rounded off) in June.
Looking ahead, major banks' forecasts on corporate fund demand showed an overall DI reading on loan demand in the October-December period will improve to minus 8 from the latest reading of minus 20 logged in the October survey.
Minus K vibration isolators incorporating Negative Stiffness technology can guarantee natural frequencies as low as 0.
The index of business prospects for the April-July quarter came to minus 44.
He also said the smaller-than-expected downward revision -- an eight-point fall from the outlook of minus 52 for the October-December period posted in the July-September survey -- was also encouraging.
The index for smaller firms having at least 10 million yen in capital worsened to minus 41.
The index has fallen deeper into minus territory since February, when it dropped to minus 4 from minus 2 in November last year, suggesting an increasingly severe employment situation amid the protracted economic downturn in Japan.
The index for manufacturers suffered its third consecutive quarterly drop to minus 49.
However, the index for all the small and midsize firms surveyed edged up to minus 40.
Business sentiment among leading Japanese companies fell into the minus column for the first time in seven quarters in the January-March term, the Ministry of Economy, Trade and Industry said Friday.
The relative percent change in behavior from 1991 to 1997 was calculated as the 1997 prevalence minus the 1991 prevalence divided by the 1991 prevalence and multiplied by 100.
Free cash flow (EBITDA minus increase in WC minus cash interest minus cash tax minus capex) rose to $448 million in 2002 from $235 million in 2001.