minocycline HCl

minocycline HCl

(min´ōsī´klēn),
n brand names: Dyancin, Minocin;
drug class: tetracycline antiinfective;
action: inhibits protein synthesis, phosphorylation in microorganisms by binding 30S ribosomal subunits, reversibly binding to 50S ribosomal subunits; bacteriostatic;
uses: syphilis,
Chlamydia trachomatis infection, gonorrhea, lymphogranuloma venereum, rickettsial infections, inflammatory acne. Also used in the treatment of some periodontal infections, generally in conjunction with mechanical therapy.
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More specifically, the 97 study participants aged 12-29 years, all with grade 3-4 moderate to severe facial acne by Investigator's Global Assessment (IGA), were placed on once-daily minocycline HCL extended release at about 1 mg/kg, clindamycin phosphate 1.
Edwards commented, "The new products introduced in 1999 included our first ANDA approval -- Minocycline HCl Capsules and our first controlled release ANDA approval -- Pentoxyfylline ER Tablets.
Warner Chilcott also received FDA approval for its 75 mg minocycline HCl product on September 15, 1999.
During the quarter we commenced shipment of our first new ANDA products, Minocycline HCl Capsules.
Edwards continued, "During the quarter we announced the receipt of our first ANDA approval from the Food and Drug Administration (FDA) to manufacture and market Minocycline HCl, an antibiotic, in 50 mg and 100 mg capsules.
PHILADELPHIA, March 29 /PRNewswire/ -- Global Pharmaceutical Corporation (Nasdaq: GLPC) today announced that it has received ANDA approval from the Food and Drug Administration (FDA) to manufacture and market Minocycline HCL 50mg and 100mg capsules, the Company's first new ANDA approval.