minocycline


Also found in: Dictionary, Thesaurus, Acronyms, Wikipedia.

minocycline

 [mĭ-no-si´klēn]
a semisynthetic broad-spectrum antibiotic of the tetracycline group; administered orally or intravenously as the hydrochloride salt

minocycline

/mi·no·cy·cline/ (mĭ-no-si´klēn) a semisynthetic broad-spectrum tetracycline antibiotic, used as the hydrochloride salt.

minocycline

(mĭn′ə-sī′klēn′, -klĭn)
n.
A broad-spectrum antibiotic, C23H27N3O7, derived from tetracycline and used usually in the form of its hydrochloride.

minocycline

A broad-spectrum tetracycline which has a longer serum half-life and achieves higher serum levels than simple tetracycline.

Indications
Acne, Lyme disease, MRSA, and other resistant microbes; it is also a recognised disease-modifying anti-rheumatic drug (DMARD).

Adverse effects
Vertigo, diarrhoea, patchy skin pigmentation, autoimmune disease.

minocycline

A TETRACYCLINE antibiotic used to treat ACNE and general infections. Brand names are Aknemin and Minocin.

minocycline

a second-generation, highly lipid-soluble derivative of tetracycline.
References in periodicals archive ?
Dermatologists often prescribe combinations of oral minocycline and topical products to treat the skin where acne conditions develop, but have never had an option for a topical minocycline solution.
In literature comparison, published results of Solodyn (oral minocycline) and recently-approved topical drugs reveal that the results observed for Minocycline Foam are superior, as shown in Table 2.
The topical administration of Minocycline Foam provides concentrated drug delivery to the infected lesion site, and leads to rapid cure, whilst avoiding the side effects common in the oral Minocycline treatment.
Moving away from retroviruses, it has been shown that minocycline is also effective against flaviviral infections.
Central nervous system side effects including light-headedness, dizziness or vertigo have been reported with minocycline therapy, but were not significant in SOLODYN clinical investigations.
For testing of the behavioral effects of vehicle or minocycline after SCI, we tested locomotor function on day 28 with the BBB locomotor rating scale and evaluated changes in mechanical and thermal nociceptive thresholds with standard thresholding paradigms.
A large, phase 4 (postmarketing) trial involving 2805 patients and 895 dentists was conducted to evaluate the use of minocycline microspheres in private practices throughout the United States.
Minocycline reduces stroke damage in late-presenting patients.
The etiology of an esophageal web in our patient cannot be exactly defined; however, it is most probably related to the local irritative effects of minocycline.
However, as with most strains of clinical origin, all the isolates tested here remained susceptible to trimethoprim-sulfamethoxazole and minocycline.
Additionally, to prevent it from binding with calcium, minocycline must be taken between meals.
Three current local chemotherapeutic agents are reviewed in this paper: doxycycline gel, chlorhexidine chip and minocycline microspheres.