One option being considered is a switch from IDT to minipool
screening, in which donations are screened in small pools (e.
Individual donor NAT is likely to be prohibitively expensive, and minipool
NAT is difficult to standardize for JEV, given the lack of data on viral loads in asymptomatic persons.
Antigen detecting card test for Malaria studies show that the risk of HIV & HCV transmission through transfusion is 1 in 2 million after introduction of Minipool
NAT (MP NAT).
To support the volume of testing needed and to conserve resources, minipool
NAT, as used for HIV and hepatitis C since 1999, was used for WNV screening.
Key elements from the past were also preserved: reception desk for the concierge, chinoiserie lounge, and black-and-white mosaic floor from the early Philipe Starck design in the club and its scandalous basement minipool
35 In our study we selected a minipool
of five individual samples.
The implicated donation was initially screened as part of a minipool
with five other donations; the MP-NAT was reactive using the Cobas TaqScreen West Nile Virus Test (Roche Molecular Systems).
NAT technology has been implemented in our service since October 2008, using minipool
samples (n = 6, 1.
This period has been estimated to be 35 days by individual sample NAT, 41 days by minipool
NAT, and 50 days by highly sensitive HBsAg immunoassays (22).
Superiority of minipool
nucleic acid amplification technology for hepatitis B virus over chemiluminescence immunoassay for hepatitis B surface antigen screening.
Gorgeous thick carpeting, a bathtub the size of a minipool
and the view from my balcony soon had me jumping for joy.
The donor had also received one unit of packed red blood cells (PRBCs) during emergency evacuation of epidural hematoma but the blood tested negative for WNV RNA by minipool
nucleic acid-amplification test (mpNAT).