minipool

minipool

(mĭ′nē-pool″)
A small sample of blood or blood products derived from a large group of blood donors. Minipools taken from 14 to 48 blood donors are screened in clinical medicine for the presence of dangerous infections, such as hepatitis B, hepatitis C, or HIV. Minipool testing is more efficient and more cost effective than the more expensive method of testing each individually donated specimen. If a minipool is negative for infection, all of its components are cleared for use. If a minipool tests positive, the individual components in the pool are tested to determine which of the donors has given a specimen that needs to be discarded.
References in periodicals archive ?
The donated plasma is subjected to a series of serological and nucleic acid amplification tests on single donation, minipool or plasma pool level exceeding regulatory requirements to ensure the maximum possible level of safety for patients.
Gorgeous thick carpeting, a bathtub the size of a minipool and the view from my balcony soon had me jumping for joy.
The donor had also received one unit of packed red blood cells (PRBCs) during emergency evacuation of epidural hematoma but the blood tested negative for WNV RNA by minipool nucleic acid-amplification test (mpNAT).
Nucleic acid-amplification minipool testing of donated blood has been successful for preventing transfusion-transmitted West Nile virus, but targeted testing of individual donations in regions with a high disease prevalence is warranted, based on two recent studies involving testing of about 7 million blood units.
The RBC units were nonreactive by minipool nucleic acid amplification testing (NAAT), but a recalled fresh frozen plasma unit associated with one of the donations was reactive by NAAT (although negative for West Nile virus-specific IgM antibody).
This supplement describes the process by which Bayer creates a minipool comprised of 96 test samples corresponding to 96 plasma donations and, then, tests each minipool using the COBAS method.
Hence, we investigated whether pooling candidate HCV samples before testing them individually, by means of a minipool RT-PCR methodology, may decrease the cost without markedly decreasing the sensitivity of the assay.
We analyzed 10,272 blood donor samples with a minipool nucleic acid amplication technique.
Previously published documents estimate that minipool NAT testing will identify HIV infectious donations 7-9 days earlier than HIV antibody tests, and identify HCV infectious donations 50-60 days earlier than HCV antibody tests.
National blood donor screening for West Nile virus (WNV) RNA using minipool nucleic acid amplification testing (MP-NAT) was implemented in the United States in July 2003.
The defaulted loans include the SS loan and a minipool of six uncrossed loans made to the same borrower.
Solvent-detergent filtered (SD-F) fresh frozen plasma and cryoprecipitate minipools prepared in a newly designed integral disposable processing bag system.