minimum inhibitory concentration


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Related to minimum inhibitory concentration: Minimum Bactericidal Concentration

minimum inhibitory concentration

minimum inhibitory concentration

The minimum concentration of an antibiotic required to inhibit bacterial growth in a clinical isolate (e.g., a blood-borne infection), which is used as a surrogate indicator of the agent’s efficacy.

minimum inhibitory concentration

Lab medicine The minimum antibiotic concentration needed to inhibit bacterial growth from a clinical isolate–eg, a bloodborne infection, which is a form of antimicrobial susceptibility testing. See Minimum bactericidal concentration.

minimum inhibitory concentration (MIC)

the lowest concentration of a chemotherapeutic agent (see CHEMOTHERAPY that will prevent growth of the test ORGANISM.
References in periodicals archive ?
The minimum inhibitory concentration (MIC) values were evaluated using the Broth Microdilution method according to standard methods [20].
Minimum inhibitory concentration (MIC) values ([micro]g/ml) of aminoglycosides in the absence and presence of EEHM and CPZ in E.
The determination of the minimum inhibitory concentration of the extract was carried out using the agar well dilution method as described by Adeniyi and Ayepola (2008).
This information, indicating how many times more expensive one drug is than another, accompanies each report of culture susceptibilities and minimum inhibitory concentrations.
The minimum inhibitory concentration (MIC) for drugs and curcumin was defined as the concentration of drug that reduced growth by 80% compared to that of organisms grown in the absence of drug.
Most authors consider the lincosamides to have a time-dependent dynamic where efficacy is related to maintaining plasma concentrations above the minimum inhibitory concentration of the pathogen for as much of the dosing interval as is possible, although that assumption seems to be based on only 2 in vitro studies.
The minimum inhibitory concentration (MIC), considered as the lowest concentration of the sample, which inhibits the visible growth of a microbe, was determined by the micro broth dilution method as described by Al-Hiari et al.
The minimum inhibitory concentration (MIC) was determined by agar dilution for the antibiotics ampicillin; tetracyclines, including doxycycline, nalidixic acid, ceftriaxone, and trimethoprim-sulfamethoxazole (T/S); fluoroquinolones, including ciprofloxacin and levofloxacin; and azithromycin and rifaximin.
When euganol was combined with the antibiotics in question there was nearly a 5-1000 fold decrease in minimum inhibitory concentration (MIC--the lowest quantity of an antibiotic that will inhibit the visible growth of a microorganism after overnight culture) of the drugs tested.
Results: The mean serum concentrations of pyrazinamide were found higher than its minimum inhibitory concentration (20 [micro]g/ml) required to inhibit the growth of tubercle bacilli from 1 to 8 h continuously.
The minimum inhibitory concentration was 200 [micro]l to 300[micro]l.

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