minimum bactericidal concentration


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Related to minimum bactericidal concentration: Minimum inhibitory concentration

minimum bactericidal concentration

The lowest concentration of an antibiotic that is bactericidal to ≥ 99.9% of an original inoculum.

MBC is a form of antibiotic susceptibility testing in which an antimicrobial agent in broth is serially diluted, or titrated in a standardised (McFarland) suspension of bacteria; tubes in which there is no growth are subcultured in an antibiotic-free growth medium. The MBC may vary as a function of certain intrinsic features of the bacterium.

minimum bactericidal concentration

Lab medicine The lowest concentration of an antibiotic that is bactericidal to ≥ 99.9% of an original inoculum. See Persistence phenomenon, Paradoxic effect, and Tolerance.

minimum bactericidal concentration

The lowest concentration of an antimicrobial that kills a defined fraction of bacteria or fungi.
Synonym: minimum lethal concentration
See also: concentration
References in periodicals archive ?
For the determination of minimum bactericidal concentration (MBC), one hundred microliter of the culture from the diluted sample of MIC assay was transferred into nutrient agar.
5 to 2 h of incubation when these phenolics were administered at twice the minimum bactericidal concentration.
Bovis 10 32(16-32) 500 (125-500) 125 500 Abbrevations MIC :minimum inhibitory concentration MBC : minimum bactericidal concentration Table 4.
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