Cumulative duration of "triple low" state of low blood pressure, low bispectral index, and low minimum alveolar concentration
of volatile anesthesia is not associated with increased mortality.
Mean minimum alveolar concentration
equivalent23 used by anaesthetists (corrected for age and specific for volatile agent) was 0.
Minimum alveolar concentrations
in man on awakening from methoxyflurane, isoflurane, ether and fluroxene anesthesia: MAC awake.
After a period of time in which the partial pressure of sevoflurane in the brain would have equilibrated with the alveolar partial pressure (6,7), the patient showed clinical signs of adequate anaesthesia and had an end-tidal sevoflurane concentration of more than 1 minimum alveolar concentration
, but the entropy monitor still indicated an awake state.
Opioid agents significantly reduce the minimum alveolar concentration
of potent inhaled anaesthetics required to facilitate intubation and improve overall intubating conditions during sevoflurane anaesthesia (5,6).
Several studies have shown a decreased maternal minimum alveolar concentration
(MAC) for inhalational agents during pregnancy (1-3).
Estimates of effect-site levels should be similar to minimum alveolar concentration
(MAC) values, which are determined after allowing time for equilibrium.