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minimal bactericidal concentration

   Also found in: Dictionary/thesaurus, Legal, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
minimal bactericidal concentration,
the lowest concentration of drug that results in a 99.9% reduction in the initial bacterial density. Compare minimal inhibitory concentration.

concentration [kon″sen-tra´shun]
1. increase in strength by evaporation.
2. the ratio of the mass or volume of a solute to the mass or volume of the solution or solvent.
3. intense mental focus.
hydrogen ion concentration see hydrogen ion concentration.
mass concentration the mass of a constituent substance divided by the volume of the mixture, as milligrams per liter (mg/l).
mean corpuscular hemoglobin concentration (MCHC) the average hemoglobin concentration in erythrocytes, conventionally expressed in “per cent,” meaning grams per deciliter of red blood cells, obtained by dividing the blood hemoglobin concentration (in g/dl) by the hematocrit (in l/l): MCHC = Hb/Hct.
minimal alveolar concentration (MAC) the concentration of anesthetic that at a pressure of 1 atmosphere produces immobility in 50 per cent of subjects exposed to a noxious stimulus.
minimal bactericidal concentration (MBC) the lowest concentration of a given antibiotic required to kill a specific organism.
minimal inhibitory concentration (MIC) the lowest concentration of a given antibiotic that inhibits the growth of a specific organism.
molar concentration the concentration of a substance expressed in terms of molarity.
concentration test a test of renal function based on the patient's ability to concentrate urine; see also fishberg concentration test.


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The patient's isolate exhibited an ampicillin minimum inhibitory concentration of 32 mg/ml, indicating the potential for achieving a therapeutic effect with high-dose therapy, and the Q/D minimal bactericidal concentration was relatively low (1.
 
 
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