minicell


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minicell

a bacterial ‘CELL’ that lacks a CHROMOSOME. It is formed from a MUTANT cell in which CELL DIVISION is aberrant, such that the SEPTUM forms towards one end of the cell, generating a small cell (‘minicell’) which has no chromosomal DNA. Minicells do not grow after they have formed, but they can be used to provide experimental TRANSCRIPTION and TRANSLATION systems if infected with DNA.
References in periodicals archive ?
The cancer cell then swallows the entire minicell," said Brahmbhatt.
The minicells are able to package, target and deliver a wide range of biologically active compounds including protein toxins, small molecule drugs, RNAi, plasmids and peptides to target cells.
According to the terms of the agreement, Lucent will provide Mobile Switching Centers based on the 5ESS(r) Switch platform, PCS Minicells, and the GALAXY Power System 4848 and Unigy(r) II batteries.
He said that these "biobots" - or minicells - could create the kind of microscopic features needed on microprocessors, or gene chips, used to test for millions of specific DNA sequences at once, reports New Scientist.
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