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milbemycin

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milbemycin
a macrolone lactone, derived from Streptomyces cyanogeneus, similar to the avermectins, effective as an anthelmintic and parasiticide. Milbemycin oxime is used for the prevention of heartworm in dogs and it has found a use in the treatment of generalized demodecosis.


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are milbemycin (sold under the brand Interceptor and Sentinel), ivermectin (sold as Heartgard and as a generic drug), and moxidectin (sold as ProHeart).
The letter stated that a labeling item for Heartgard Plus (ivermectin/pyrantel) compared the drug with milbemycin oxime (MBO) products and selamectin in treatment of canine parasites with zoonotic potential that may "call into question the efficacy" of MBOs in the treatment of Ancylostoma caninum.
 
 
 
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