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migration inhibition test

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migration inhibition test
n.
An in vitro method of testing for cellular immune response in which macrophages are placed in a capillary tube containing a specific antigen.

migration
movement of living things from one place to another by their own volition. Also used to describe movement of nonliving biological material, e.g. migration of protein in electrophoretic media.

migration inhibition factor
see leukocyte migration-inhibition factor, macrophage inhibition factor, migration inhibition test (below).
migration inhibition test
an in vitro test for detection of cell-mediated immunity (or delayed hypersensitivity) in which peritoneal exudate cells (lymphocytes and macrophages) are packed in capillary tubes and placed in a medium; if the medium contains an antigen to which the lymphocytes are primed, macrophage migration from the tubes is inhibited by lymphokines, particularly macrophage inhibiting factor, released by the antigen stimulated lymphocytes.


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