microvillus inclusion disease

microvillus inclusion disease

[MIM*251850]
a condition that begins at birth with persistent watery diarrhea and life-threatening malabsorption associated with villous atrophy and crypt hypoplasia in the small bowel; electron microscopy reveals microvillus inclusions in enterocytes.

microvillus inclusion disease

A rare congenital disorder in which newborns or infants develop severe watery diarrhea (caused by intestinal malabsorption) resulting in dehydration, metabolic disarray, and malnutrition. It can be treated with small bowel transplantation when donor organs are available. Synonym: microvillous atrophy
References in periodicals archive ?
Sameerah was suffering from microvillus inclusion disease and was very seriously ill," he said.
A Midlands health official said the only child affected was six-year-old schoolgirl Sameerah Ahmad, of Gillott Road, Edgbaston, who died at Birmingham Children's Hospital on June 29, suffering with severe rare condition Microvillus Inclusion Disease, which affects the lining of the small intestine.
Sameerah, who lived in Edgbaston with her parents and attended the specialist Mayfield School in the city, was born with a rare, life-threatening disease called microvillus inclusion disease, which left her liable to contracting infections.
Hospital consultant Dr Gale Pearson said Sameerah had been born with microvillus inclusion disease, which affects one in 10,000, adding: "It can be life threatening.
Destruction of villi and microvilli of the intestines by oral insulin containing biochemical addictives can lead to malabsorption of nutrients and persistent osmotic diarrhea, often accompanied by fever, as seen in celiac disease and Microvillus Inclusion disease, etc.
It is the second death following sixyear-old Sameerah Ahmad, of Gillott Road, Edgbaston, who died at Birmingham Children's Hospital while infected with the virus on June 26, but was seriously ill with Microvillus Inclusion Disease affecting the lining of the small intestine.
Little Hollie O'Riordan was just one of 50 people in the world who suffered from Microvillus Inclusion Disease.
It is the second death following six-year-old Sameerah Ahmad, of Gillott Road, Edgbaston, who died at Birmingham Children's Hospital while infected with the virus on June 26, but was seriously ill with Microvillus Inclusion Disease affecting the lining of the small intestine.
Sameerah Ahmad, who was born with Microvillus Inclusion Disease, which is an extremely rare condition affecting the lining of the small intestine, died at Birmingham's Children's Hospital on Friday evening.
Hollie O'Riordan, from Ballyvolane, Cork, is one of just 50 people in the world with Microvillus Inclusion Disease, a rare intestinal disorder.
The inquest was told Sameerah, who lived with her parents in Edgbaston, and was a pupil at Mayfield School in Handsworth, was born with microvillus inclusion disease, which causes severe and often lifethreatening diarrhoea.