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microsomal enzymes

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microsomal enzymes
[-sō′məl]
a group of enzymes associated with a certain particulate fraction of liver homogenate that plays a role in the metabolism of many drugs.


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11beta-Hydroxysteroid dehydrogenases (11beta-HSD) are microsomal enzymes that catalyze the conversion of active glucocorticoids (GC) to their inactive 11-dehydro products and vice versa.
Polyphenols and Tocotrienols have been shown to inhibit Phase 1 microsomal enzymes, and the lipoprotein fraction of nature foods has been shown to inhibit abnormal cell prolifeation.
The purpose of the present investigation is twofold: to group PCB congeners based on their potential to induce microsomal enzymes in animals; and to examine the relation between neonatal TSH and prenatal exposure to PCB congeners grouped according to their structure and potential mechanisms of actions.
 
 
 
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