microsomal enzyme system

microsomal enzyme system

A collection of enzymes in the smooth endoplasmic reticulum of liver cells that modify molecules to make them more POLAR and less lipid-soluble.
References in periodicals archive ?
For assay after incubation of chemicals with the rat liver microsomal enzyme system, a sample from the incubation mixture was subjected to the assay as described above.
More often, however, the barbiturates cause a marked increase in the microsomal enzyme system to accelerate the metabolism of other drugs including the sedative-hypnotics themselves.