microphthalmia

(redirected from microphthalmus)
Also found in: Dictionary, Encyclopedia.
Related to microphthalmus: microphthalmia

microphthalmos

 [mi″krof-thal´mus]
a developmental defect causing moderate or severe reduction in size of the eye.

mi·croph·thal·mos

(mī'krof-thal'mos),
Abnormal smallness of the eye.
[micro + G. ophthalmos, eye]

microphthalmia

A congenital reduction in eye size, with the ocular bulb measuring 1/2 of the normal volume in extreme cases, due to an abnormal development of the optic vesicle in the optic cup.

Aetiology
• Congenital—e.g., encephalo-ophthalmic dysplasia, focal dermal hypoplasia, Hallermann-Streiff syndrome, incontinentia pigmenti, Lenz microphthalmia syndrome, retinopathy of prematurity, trisomy 13-15.
• Infectious—e.g., CMV, herpes, rubella, toxoplasmosis.
• Toxins—e.g., foetal alcohol syndrome.

Incidence
14/105; 3–11% of all cases of blindness.

microphthalmia

A congenital ↓ in eye size, with the ocular bulb measuring12 of the normal volume in extreme cases, due to an abnormal development of the optic vesicle in the optic cup, which may be
1. Congenital, as in encephalo-ophthalmic dysplasia, focal dermal hypoplasia, Hallermann-Streiff syndrome, incontinentia pigmenti, Lenz's microphthalmia syndrome, retinopathy of prematurity, trisomy 13-15 or.
2. Infectious–eg, CMV, rubella, toxoplasmosis. See TORCH.

microphthalmia

Congenital anomaly in which the eyeball is abnormally small and often deeply set in a small orbit. It is typically hyperopic. Syn. microphthalmos; microphthalmus. When there is no other abnormality (e.g. coloboma of the iris, microphthalmos with cyst), the condition is called nanophthalmos (Fig. M10). See anophthalmia; monophthalmia; pseudoptosis.
Fig. M10 Right eye microphthalmos (From Kanski 2007, with permission of Butterworth-Heinemann)enlarge picture
Fig. M10 Right eye microphthalmos (From Kanski 2007, with permission of Butterworth-Heinemann)

mi·croph·thal·mos

, microphthalmia (mī'krof-thal'mŏs, -mē-ă)
Abnormal smallness of the eye.
[micro- + G. ophthalmos, eye]

microphthalmia

References in periodicals archive ?
cholinergic chronicle (2) Chromium microphthalmus W2 mesorchium (4) Cobalt blackout