micropapillary urothelial carcinoma

micropapillary urothelial carcinoma

A uncommon variant of urothelial (transitional cell) carcinoma that presents in older (average age 76) adults, more commonly in men, which is histologically high grade, deeply invasive (into muscularis propria) and metastastatic, variably accompanied by in situ carcinoma.

DiffDx
Metastatic micropapillary carcinoma, papillary (e.g., renal cell) carcinoma.

Management
Immediate radical cystectomy.

Prognosis
Poor: all patients die within two years.
References in periodicals archive ?
37,14] Micropapillary urothelial carcinoma is a unique variant of urothelial carcinoma that comprises 0.
Outcome of patients with micropapillary urothelial carcinoma following radical cystectomy: ERRBB2 (HER2) amplification identifies patients with poor outcome.
Micropapillary urothelial carcinoma is a rare aggressive subtype of transitional cell carcinoma.
Micropapillary urothelial carcinoma is recognized as a rare and aggressive variant of urothelial carcinoma, which often presents at a high-stage.
Outcome of patients with micropapillary urothelial carcinoma following radical cystectomy: ERBB2 (HER2) amplification identifies patients with poor outcome.
Invasive micropapillary urothelial carcinoma of the bladder.
8) A direct extension of a micropapillary urothelial carcinoma was highly unlikely.
Micropapillary urothelial carcinoma (MPUC) is a rare, clinically aggressive histologic variant of urothelial carcinoma (UC).
Micropapillary urothelial carcinoma was initially described as a histologic variant of conventional urothelial carcinoma with an aggressive clinical course.
Emerging concepts in micropapillary urothelial carcinoma.
Micropapillary urothelial carcinoma of the urinary bladder: a clinicopathological analysis of 72 cases.
Micropapillary urothelial carcinoma of the upper urinary tract: clinicopathologic study of five cases.