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micronucleus
(redirected from micronuclei)

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
micronucleus /mi·cro·nu·cle·us/ (-noo´kle-us)
1. in ciliate protozoa, the smaller of two types of nucleus in each cell, which functions in sexual reproduction; cf. macronucleus.
2. a small nucleus.

mi·cro·nu·cle·us (mkr-nkl-s)
n.
1. A minute nucleus.
2. The smaller of two nuclei in ciliate protozoans that contains genetic material and functions in reproduction.

micronucleus
[-no̅o̅′klē·əs]
1 a small nucleus.
2 the smaller of two nuclei in some protozoa. It functions in sexual reproduction. Compare macronucleus.

micronucleus [mi″kro-noo´kle-us]
1. in ciliate protozoa, the kinetoplast, the smaller of two types of nucleus in each cell, which functions in sexual reproduction.
2. a small nucleus.

micronucleus
1. in ciliate protozoa, the kinetoplast, the smaller of two types of nucleus in each cell, which functions in sexual reproduction.
2. a small nucleus.
3. nucleolus.


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A number of in vitro mammalian cell-based genotoxicity assays have been developed, including test methods for identifying micronuclei and mutations of marker genes (Bonassi et al.
The researchers looked at three standard indicators of chromosomal damage: structural chromosomal aberrations (breaks in chromosomes), micronuclei (small nuclei consisting of chromosome fragments produced by breakage or whole chromosomes lost from the main nucleus after the cell divides), and sister chromatid exchanges (exchanges of genetic material between a pair of identical chromosomes).
Rochester, NY) has patented a method for the enumeration of mammalian cell micronuclei, while distinguishing micronuclei from the chromatin of dead and dying cells.
 
 
 
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