microglia

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Related to microglial: Astrocytes, Oligodendrocytes

microglia

 [mi-krog´le-ah]
non-neural cells forming part of the adventitial structure of the central nervous system. They are migratory and act as phagocytes of waste products of the nervous system. adj., adj microg´lial.

mi·crog·li·a

(mī-krog'lē-ă), This word is grammatically singular. Avoid the mispronunciation microgli'a.
Small neuroglial cells of the central nervous system, originating in the bone marrow, that may become phagocytic in areas of neural damage or inflammation.
[micro- + G. glia, glue]

microglia

/mi·crog·lia/ (mi-krog´le-ah) small nonneural cells forming part of the supporting structure of the central nervous system. They are migratory and act as phagocytes to waste products of nerve tissue.microg´lial
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Microglia.

microglia

(mī′krō-glē′ə, -glī′-)
n.
(used with a pl. verb) Any of the small neuroglial cells of the central nervous system having long processes and amoeboid and phagocytic activity at sites of neural damage or inflammation.

microglia

[mīkrog′lē·ə]
Etymology: Gk, mikros + glia, glue
small, migratory interstitial cells that form part of the central nervous system. They have various forms and slender, branched processes. Microglia serve as phagocytes that collect waste products of the nerve tissue of the body. Also called Hortega cells, mesoglia.
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Microglia

microglial cell

A perivascular bone-marrow-derived cell native to the CNS, belonging to the mononuclear phagocytic system (e.g., monocytes, macrophages, dendritic cells and granulocytes), which presents antigens in an MHC-class-II restricted context.

mi·crog·li·a

(mī-krog'lē-ă)
Small neuroglial cells, possibly of mesodermal origin, which may become phagocytic, in areas of neural damage or inflammation.
Synonym(s): Hortega cells.
[micro- + G. glia, glue]
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MICROGLIA

microglia

(mi-krog'le-a) [? + glia, glue]
Cells of the central nervous system (CNS) present between neurons or next to capillaries. These cells may function as macrophages when they migrate to damaged CNS tissue.
See: gitter cell; illustration

microglia

Neurological connective tissue MACROPHAGES. Compare MACROGLIA.

Hortega,

Pio del Rio, Spanish neurohistologist in South America, 1882-1945.
Hortega cells - small neuroglial cells that may become phagocytic in areas of neural damage or inflammation. Synonym(s): microglia
Hortega neuroglia stain - one of several silver carbonate methods to demonstrate astrocytes, oligodendroglia, and microglia.

microglia

scavenging reticuloendothelial cells within nerve tissue

microglia

non-neural cells forming part of the adventitial structure of the central nervous system. They are migratory and act as phagocytes of waste products of the nervous system.
References in periodicals archive ?
Induction of protein kinase C substrates, myristoylated alaninerich C kinase substrate (MARCKS) and MARCKSrelated protein (MRP), by amyloid beta-protein in mouse BV-2 microglial cells.
When the intake of saturated fats is chronically high, this microglial sensory network may be hijacked, and this has the potential to mediate increased food consumption and promote more rapid weight gain.
Microglial proliferation, as visualized with Lycopericum esculentum lectin, was evident in brains of 113LBoPrP-Tg037 mice but not in age-matched control mice.
Consistent with this suggestion, development of allodynia in the contralateral uninjured limb following a unilateral burn injury in rats is paralleled by development of hyperexcitability of dorsal horn neurons and activation of microglia on both sides of the spinal cord [16]; minocycline, which inhibits microglial activation, attenuates allodynia on both sides of the body in this model [26].
6) Pathological studies of these cases have revealed microglial cells as well as microabscesses with neutrophils and macrophages.
1,4,7,8) The histopathologic findings of Bickerstaff brainstem encephalitis do show chronic perivascular inflammation with activated microglia similar to CLIPPERS, but it is usually accompanied by edema and occasional microglial nodules.
Later on it was reported that minocycline was also effective in adjunct therapy for acquired immunodeficiency syndrome (AIDS) dementia by virtue of its anti-inflammatory effect on the microglial cells thereby inhibiting their activation and also inhibiting virus production from these cells (20).
Understanding the signaling pathways responsible for microglial activation is crucial for the prevention of microglia-enhanced neurodegeneration.
Pomper of the Johns Hopkins School of Medicine in Baltimore will assess imaging microglial activation in neuropsychiatric lupus; Dr.
But recent research indicates that luteolin improves cognitive health by acting directly on the microglial cells to reduce their production of inflammatory cytokines in the brain.
They also may do so indirectly by altering astrocyte, oligodendrocyte and microglial functions.
As part of the three-year project, which is funded by a grant from the Alzheimer's Research Trust, Emma will transform stem cells from patients into microglial cells - types of brain cell acting as the brain's immune system.