microfollicular

microfollicular

/mi·cro·fol·lic·u·lar/ (-fah-lik´u-lar) pertaining to or characterized by small follicles.
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Microfollicular adenomatoid nodule and follicular adenoma are the frequent thyroid gland lesions presenting with follicular pattern on routine histopathological examination.
The microfollicular variant shows paucity of colloid.
On cut section two were completely solid and remaining two were both solid and cystic in nature filled with brown colored fluid, microscopy of all 4 cases showed microfollicular pattern, along with trabecular pattern in 2 cases.
Thyroid follicular hyperplasia was histologically observed in all birds examined, while granulomatous thyroiditis and microfollicular adenoma were observed in 2 birds, respectively.
Biopsy reports were recorded as indicating a benign lesion if colloid, macrophages and follicular cells were reported, and as suspicious for follicular carcinoma if a microfollicular pattern with cellular overlapping or a predominance of Hurtle cells was seen.
A second nodule that was previously identified as a hypogenic nodule on the thyroid ultrasonography was found to be a microfollicular adenoma.
14 cases were diagnosed cytologically as benign follicular cells, histopathologically were diagnosed as follows: 2 cases microfollicular adenoma, 2 cases as lymphocytic thyroiditis 8 cases as diffuse hyperplaslic thyroid tissue and 2 cases as follicular carcinoma two cases were diagnosed cytologically as undifferentiated malignant cells histopathologically was diagnosed as malignant lymphoma.
Insular carcinoma of the thyroid: Report of a case with intact insulae and microfollicular structures.
Follow-up thyroid excision of the case in Figure 1, showing thyroid nodular hyperplasia with a predominant microfollicular growth pattern (hematoxylin-eosin, original magnification X100).
The features analyzed included cellularity, microscopic pattern (Monolayered sheets, syncytial clusters, microfollicular pattern, papillary fronds and single cell distribution), nuclear features (Anisonucleosis, nucleomegaly, fine powdery chromatin, grooves, intranuclear cytoplasmic inclusions, irregular nuclear membrane and nucleoli), colloid characteristics (Thick or thin ) and psammoma bodies.
Follicular neoplasms are characterized by follicular cells arranged in a microfollicular, solid to trabecular pattern enclosed by a distinct capsule.