microelectronic array

microelectronic array

A system used for molecular diagnostic genotyping that uses microelectrodes to concentrate DNA samples and accelerate probe hybrisation. Microelectronic arrays have been developed for DNA hybridisation analysis of point mutations, single nucleotide polymorphisms, short tandem repeats and gene expression. In addition to a variety of molecular biology and genomic research applications, such devices are also used for infectious disease detection, genetic and cancer diagnostics, and pharmacogenomic applications; they can be used to detect DNA, RNA, proteins, enzymes, antibodies and cells.
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Among the available approaches, a microelectronic array technology has been developed for DNA hybridization analysis of mutations/ single-nucleotide polymorphisms (SNPs) (1-4).
Analysis of clinically relevant single-nucleotide polymorphisms by use of microelectronic array technology.
Active microelectronic array system for DNA hybridization, genotyping and pharmacogenomic applications.
The company manufactures and sells the DEPArray[TM] platform, which is a lab-on-a-chip technology to isolate and manipulate cells in suspension with a microelectronic array.
Alternatives include bead array technologies (39, 40) and microelectronic array devices (41, 42), which yield information in seconds or minutes rather than hours or days, that allow for rapid estimation of gene expression.
Microelectronic array devices and techniques for electric field enhanced DNA hybridization in low-conductance buffers.
The company manufactures and sells the DEPArray[TM] platform which is based on the principle of dielectrophoresis to isolate and manipulate cells in suspension with a microelectronic array.
Microelectronic array technology was recently introduced for SNP analysis (11-15).
In addition, we show that the microelectronic array technology is accurate in facilitating clinically important analyses.
Alternatively, the method we describe is highly accurate and uses automated microelectronic array technology analysis.
The NanoChip microelectronic array technology for analysis of the FVL SNP provides extremely high accuracy, readily discriminating between wild types, heterozygotes, and homozygotes, as confirmed by comparison with DNA sequencing.
is based in Bologna Italy and has developed the DEPArray[TM] platform using the principles of dielectrophoresis to isolate and manipulate cells in suspension with a microelectronic array.
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