The three inventions Neuralstem has licensed from Cleveland Clinic are: a Stabilized Platform and Microelectrode Recording
Guidance Validation; a Floating Cannula for Spinal Cord Therapeutic Injection; and a Spinal Platform and Methods for Delivering a Therapeutic Agent to a Spinal Cord Target.
The benefits and risks of using microelectrode recording
(MER) can be related to the number of electrode passes made to localize the STN.
This is our first surgery with the NeuroMate(TM) System utilizing single tract microelectrode recording
This highly specialized company strives to provide neurosurgeons and neuroscientists with all of their Microelectrode Recording
needs from A to Z.
Comparable in size to a briefcase, the StimPilot System replaces use of stand-alone, refrigerator-sized surgical navigation and microelectrode recording
(MER) systems that represent significant upfront capital expenditures for the hospital.
A standard part of the cingulotomy procedure involves microelectrode recordings
of the activity of single neurons in the area where the lesion is to be placed.
The next set of chapters covers anesthesia, sterotactic surgery with and without microelectrode recordings
, implantation of multiple electrodes and robotic techniques, frameless functional stereotactic approaches, and deep brain stimulation for tremor and for dysteria.
Innovations in the field of brain imaging, interactive computer guidance devices, and single cell microelectrode recordings
, are all helping drive the effectiveness, and hence growth of neurostimulation.
Working in collaboration with Associate Professor Gordon Baltuch, Zaghloul and Kahana used microelectrode recordings
obtained during deep brain stimulation surgery of Parkinson's patients to study neuronal activity in the SN, the midbrain structure that plays an important role in movement, as well as reward and addiction.
SNI's comprehensive diagnostic and surgical capabilities include: -- Integrated, GPS-like guidance systems built into every OR that help surgeons navigate in critical areas of the brain during operations -- Intraoperative MRI and CT scanners and 3-D angiography that provide vital images during surgery -- Brain-mapping capabilities to identify areas of critical brain function through microelectrode recordings
of brain tissue -- Interventional neuroradiology techniques to block blood flow to tumors or blood-vessel malformations prior to surgery, place stents (small wire mesh tubes used for keeping vessels open) in narrowed brain arteries and repair cerebral aneurysms
With microelectrode recordings
, more penetrations of the brain have to be made and this increases the risk of intracranial hemorrhage.
Vanderbilt University, Nashville, Tennessee, Deciphering neural codes for perception using chronic, multi-site microelectrode recordings
from auditory and multisensory cortical fields in behaving monkeys, Principal Investigator: Jon Kaas, Co-Principal Investigator: Troy Hackett, $450,000 over three years.