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microdialysis

   Also found in: Encyclopedia, Wikipedia 0.01 sec.
microdialysis,
n a technique for measuring extracellular concentrations of substances in tissues, usually in vivo, by means of a small probe equipped with a semipermeable membrane. Substances may also be introduced into the extracellular space through the membrane.


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Louis used a method called microdialysis to measure the levels of amyloid-beta protein in the fluid between brain cells of mice.
Published in the journal Science, one of the studies saw microdialysis experiments being conducted on mice, and found that extracellular amyloid-beta levels in the brain fall during slumber and rise with wakefulness.
A model to evaluate the pharmacokinetic and pharmacodynamic variables of extendedrelease products using in vivo tissue microdialysis in humans: Bupivacaine-loaded microcapsules.
 
 
 
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