G]); IRF, immature reticulocyte fraction; LHD, low hemoglobin density; MAF, microcytic
anemia factor; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; MPV, mean platelet volume; MRV, mean reticulocyte volume; MSCV, mean sphered cell volume; NA, not available; PDW, platelet distribution width; RBC, red blood cell; RDW, red cell distribution width; RDWR, reticulocyte distribution width; RSF, red cell size factor.
The most important differential diagnoses of microcytic
and/or hypochromic red cell indices are thalassaemia trait and anaemia of chronic disease.
It also displays an estimate of percentages of microcytic
, macrocytic and hypochromic red cells.
Most (80%) of the 50 children investigated were anemic, and half of those had microcytic
anemia characterized by alterations of the hemoglobin, hematocrit, and globular volume.
Patients who have developed iron deficiency, manifested by microcytic
, hypochromic red cells, decreased transferrin saturation, and absent bone marrow iron, usually respond to oral or parenteral iron administration (Richardson & Weinstein, 1970).
If two of the four loci are affected, the condition is called alpha thalassemia trait with mild microcytic
and her contributors introduce hematology and its basic laboratory practice, including standard precautions, working from hematopoiesis to the complete blood count, understanding red blood cell production and its function and relevant red cell morphology, hemoglobin function and principles of hemolysis, red cell disorders such as the microcytic
and macrocytic anemias, normochromic anemias, biochemical and membrane disorders and genetic disorders, white cell disorders including leukemias, hemostasis and disorders of coagulation, and a complete set of laboratory procedures.
The patient was found to have microcytic
anemia, and further workup revealed a beta-thalassemia trait.
Routine labs were drawn and revealed a microcytic
anemia and an elevated alkaline phosphatase to 189.
A panoply of manifestations ranging from microcytic
anemia, abdominal pain, seizures, and even death may ensue.
Blood was withdrawn from the offspring, via tail bleeds, twenty-four days after birth to determine lead levels, to perform differential counts, to observe lead-induced red blood cell basophilic stippling, to monitor microcytic
anemia, and to quantify total plasma protein levels.
The homozygous, recessive hereditary erythroblastic anemia mouse (hea) is characterized by a hypochromic, microcytic
anemia that is lethal 5-7 days after birth.