miRNA


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Related to miRNA: Sirna

miRNA

Abbreviation for microribonucleic acid.

miRNA

abbr.
microRNA

microRNA

Any of a group of short (generally 21 to 24 nucleotides in length), non-coding RNA molecules which fold upon themselves (“hairpins”) and are usually cleaved from larger hairpin-containing RNA (itself often processed from some portion of mRNA).

MiRNA is conserved through evolution and plays a role in RNA interference, destroying mRNA made by specific genes, suppressing gene expression and controlling translation of target mRNAs, thereby regulating critical aspects of plant and animal development.

miRNA

MicroRNA: short nucleotide sequences that regulate DNA expression but are not themselves transcribed.
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Chronic intermittent ethanol exposure and its removal induce a different miRNA expression pattern in primary cortical neuronal cultures.
The length distribution showed that more than 90% of the small RNA sequences were primarily distributed in 19 to 24 nt, which is consistent with the typical size of mature mammalian miRNA from Dicer digestion products (Zhang et al.
Silence Therapeutics Mirna Therapeutics Thomas Christely/Max Herrmann Paul Lammers, MD +49 30 9489 2800/+44 20 7491 6520 +1 512 901 0909 t.
Mirna and Farah chose to take active part in society through CCPA Lebanon because of the reputation of the organization in the area.
Most of the miRNA regulation by RNA-binding proteins (RBPs) is at the post-transcriptional level.
5,6) Similarly, miRNA 223 promotes granulopoiesis by enhancing the expression of transcription factor C/EPB-[alpha], a positive regulator of granulopoiesis.
Mendell and his colleagues focused on a particular miRNA called miR-26a, chosen because it was much less abundant in liver cancer cells than in normal liver cells.
Luminex's FlexmiR line of products is the only miRNA platform designed for both broad panel screens and smaller target validations.
In fact, Mirna found her learning experience at Parkgate Learning Centre so enjoyable, she is now studying for a Higher National Certificate in Administration and Information Technology at college.
Since each miRNA appears to regulate the expression of tens to hundreds of different genes, miRNAs can function as "master-switches," efficiently regulating and coordinating multiple cellular pathways and processes.
A brief look at the market suggests that cancer is the most researched topic and regions such as United States, United Kingdom, France, Israel and China are the major players interested in evaluating the role played by miRNA.
In this Q&A, we ask 4 miRNA experts with an interest in coronary artery disease to shed light on the utility of circulating miRNA in testing for AMI and to provide insight into the benefits, applications, challenges, and limitations of this potentially powerful new tool.