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An organophosphorus compound effective against immature and mature stages of Schistosoma haematobium, but ineffective against other species of Schistosoma in humans.
metrifonateAn organophosphate that is an irreversible inhibitor of acetylcholinesterase. Metrifonate had some currency for treating Schistosoma haematobium schistosomiasis, but proved less effective than praziquantel and is thus no longer used for this indication. It was being developed for Alzheimer's dementia, but was withdrawn due to adverse effects (respiratory paralysis and defects in neuromuscular transmission).
metrifonateNeurology A cholinesterase inhibitor which is anthelmintic and used to manage dementia. See Alzheimer's disease.
metrifonateAn organophosphorus CHOLINESTERASE inhibitor drug used to kill the worms in SCHISTOSOMIASIS, especially Schistosoma haematobium.
an organophosphorus insecticide. See trichlorfon.