methylases

methylases

host cell enzymes that introduce methyl groups into bases of DNA. In prokaryotic cells two methyl groups are introduced into the palindromic sequences by the restriction endonucleases that recognize the palindrome; when methylated, the restriction enzyme does not cut the DNA so that methylation protects host cell DNA from cleavage.
References in periodicals archive ?
Nomenclature of plasmid-mediated 16S rRNA methylases responsible for panaminoglycoside resistance.
However, its unique structure may serve in the future as a prototype for new molecules resistant to both NDM and methylases [27].
Distribution of genes encoding erythromycin ribosomal methylases and an erythromycin efflux pump in epidemiologically distinct groups of staphylococci.
In the first step of this cycle, the SAM-dependent methylases that use SAM as a substrate produce S-adenosyl homocysteine as a product.
The resistance is via three related genes, ermA, ermB, and ermC, which produce methylases that alter the targeted ribosome by methylating it.
Site-specific methylases induce the SOS DNA repair response in Escherichia coli.
The activity of endogenous methylases in human placenta increased steadily with weeks of gestation, suggesting that increased formation of methyltransferases might occur during pregnancy (Paik et al.
Like other methylases, Dam chemically coats DNA with clusters of atoms known as methyl groups.
aureus is usually caused either by ribosomal modification mediated by 23S rRNA methylases encoded by erm genes, or by active efflux of the antimicrobial agent by an ATP-dependent pump encoded by msrA gene.
In that study, ~2-5% of CCGG sites were fully methylated, suggesting that nuclear methylases enter a subset of the mitochondria.